Synthesis and antimicrobial activity of silver-doped hydroxyapatite nanoparticles.
The synthesis of nanosized particles of Ag-doped hydroxyapatite with antibacterial properties is of great interest for the development of new biomedical applications. The aim of this study was the evaluation of Ca(10-x)Ag(x)(PO4)6(OH)2 nanoparticles (Ag:HAp-NPs) for their antibacterial and antifunga...
| Publicado en: | BioMed Research International Vol. 2013; pp. 916218 - 916219 |
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| Autores principales: | , , , , , |
| Formato: | research Journal Article |
| Publicado: |
Wiley-Blackwell
2013
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=104287172&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 104287172 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 23146133 FT2T jtl: BioMed Research International issn: 23146133 maglogo: N pubinfo: dt: 2013 vid: 2013 pid: 480 pub: Wiley-Blackwell place: Malden, Massachusetts artinfo: ui: 104287172 104287172 2012116765 NLM23509801 PMC3591194 104287172 ppf: 916218 ppct: 1 formats: fmt: @attributes: type: P tig: atl: Synthesis and antimicrobial activity of silver-doped hydroxyapatite nanoparticles. aug: au: Ciobanu, Carmen Steluta Iconaru, Simona Liliana Chifiriuc, Mariana Carmen Costescu, Adrian Le Coustumer, Philippe Predoi, Daniela affil: Department of Multifunctional Materials and Structures Laboratory, National Institute of Materials Physics, 105 Bis Atomistilor, P.O. Box MG 07, 077125 Magurele, Romania. sug: subj: Antiinfective Agents Pharmacodynamics Minerals Nanoparticles Silver Biofilms Drug Design Fungi Drug Effects Gram-Negative Bacteria Drug Effects Gram-Positive Bacteria Drug Effects Microbial Culture and Sensitivity Tests Microscopy, Electron, Scanning Microscopy, Electron Spectrophotometry, Infrared X-Rays Human ab: The synthesis of nanosized particles of Ag-doped hydroxyapatite with antibacterial properties is of great interest for the development of new biomedical applications. The aim of this study was the evaluation of Ca(10-x)Ag(x)(PO4)6(OH)2 nanoparticles (Ag:HAp-NPs) for their antibacterial and antifungal activity. Resistance to antimicrobial agents by pathogenic bacteria has emerged in the recent years and became a major health problem. Here, we report a method for synthesizing Ag doped nanocrystalline hydroxyapatite. A silver-doped nanocrystalline hydroxyapatite was synthesized at 100°C in deionised water. Also, in this paper Ag:HAp-NPs are evaluated for their antimicrobial activity against gram-positive and gram-negative bacteria and fungal strains. The specific antimicrobial activity revealed by the qualitative assay is demonstrating that our compounds are interacting differently with the microbial targets, probably due to the differences in the microbial wall structures. pubtype: Academic Journal doctype: research Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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