The phenotype of the Cryptococcus-specific CD4+ memory T-cell response is associated with disease severity and outcome in HIV-associated cryptococcal meningitis.

Background: Correlates of immune protection in patients with human immunodeficiency virus (HIV)-associated cryptococcal meningitis are poorly defined. A clearer understanding of these immune responses is essential to inform rational development of immunotherapies.Methods: Cryptococcal-specific perip...

Descripción completa

Detalles Bibliográficos
Publicado en:Journal of Infectious Diseases Vol. 207; no. 12; pp. 1817 - 1829
Autores principales: Jarvis, Joseph N, Casazza, Joseph P, Stone, Hunter H, Meintjes, Graeme, Lawn, Stephen D, Levitz, Stuart M, Harrison, Thomas S, Koup, Richard A
Formato: research randomized controlled trial Journal Article
Publicado: Oxford University Press / USA Jun2013
Acceso en línea:Ver este registro en EBSCOhost