Lovastatin Production by Aspergillus terreus Using Agro-Biomass as Substrate in Solid State Fermentation.
Ability of two strains of Aspergillus terreus (ATCC 74135 and ATCC 20542) for production of lovastatin in solid state fermentation (SSF) using rice straw (RS) and oil palm frond (OPF) was investigated. Results showed that RS is a better substrate for production of lovastatin in SSF. Maximum producti...
| Publicado en: | Journal of Biomedicine & Biotechnology Vol. 2012; pp. 1 - 12 |
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| Autores principales: | , , , , , |
| Formato: | pictorial research tables/charts tracings Journal Article |
| Publicado: |
Wiley-Blackwell
2012
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=104297824&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 104297824 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 11107243 137K jtl: Journal of Biomedicine & Biotechnology issn: 11107243 maglogo: N pubinfo: dt: 2012 vid: 2012 pid: 480 pub: Wiley-Blackwell place: Malden, Massachusetts artinfo: ui: 104297824 104297824 2011906746 NLM23118499 PMC3478940 104297824 ppf: 1 ppct: 11 formats: fmt: @attributes: type: P tig: atl: Lovastatin Production by Aspergillus terreus Using Agro-Biomass as Substrate in Solid State Fermentation. aug: au: Faseleh Jahromi, Mohammad Juan Boo Liang Yin Wan Ho Mohamad, Rosfarizan Yong Meng Goh Shokryazdan, Parisa affil: Laboratory of Industrial Biotechnology, Institute of Bioscience, Universiti Putra Malaysia, 43400 Serdang, Malaysia sug: subj: Lovastatin Methane Adverse Effects Aspergillus Metabolism Energy-Generating Resources Plants Fermentation Descriptive Statistics Data Analysis Software Microscopy, Electron, Scanning Molecular Structure Particle Size Funding Source ab: Ability of two strains of Aspergillus terreus (ATCC 74135 and ATCC 20542) for production of lovastatin in solid state fermentation (SSF) using rice straw (RS) and oil palm frond (OPF) was investigated. Results showed that RS is a better substrate for production of lovastatin in SSF. Maximum production of lovastatin has been obtained using A. terreus ATCC 74135 and RS as substrate without additional nitrogen source (157.07 mg/kg dry matter (DM)). Although additional nitrogen source has no benefit effect on enhancing the lovastatin production using RS substrate, it improved the lovastatin production using OPF with maximum production of 70.17 and 63.76 mg/kg DM for A. terreus ATCC 20542 and A. terreus ATCC 74135, respectively (soybean meal as nitrogen source). Incubation temperature,moisture content, and particle size had shown significant effect on lovastatin production (P < 0.01) and inoculums size and pH had no significant effect on lovastatin production (P > 0.05). Results also have shown that pH 6, 25°C incubation temperature, 1.4 to 2mm particle size, 50% initial moisture content, and 8 days fermentation time are the best conditions for lovastatin production in SSF. Maximum production of lovastatin using optimized condition was 175.85 and 260.85 mg/kg DM for A. terreus ATCC 20542 and ATCC 74135, respectively, using RS as substrate. pubtype: Academic Journal doctype: pictorial research tables/charts tracings Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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