Methyl Mercury Exposure at Niigata, Japan: Results of Neurological Examinations of 103 Adults.
Background. Large-scale poisonings caused by methyl mercury (MeHg) have occurred in Japan (Minamata in the 1950s andNiigata in the 1960s) and Iraq (in the 1970s). The current WHO neurological risk standard for adult exposure (hair level: 50 μg/g) was based partly on evidence from Niigata which did n...
| Publicado en: | Journal of Biomedicine & Biotechnology Vol. 2012; pp. 1 - 8 |
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| Autores principales: | , , , , , |
| Formato: | research tables/charts Journal Article |
| Publicado: |
Wiley-Blackwell
2012
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=104297944&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 104297944 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 11107243 137K jtl: Journal of Biomedicine & Biotechnology issn: 11107243 maglogo: N pubinfo: dt: 2012 vid: 2012 pid: 480 pub: Wiley-Blackwell place: Malden, Massachusetts artinfo: ui: 104297944 104297944 2011906867 NLM22888201 PMC3410367 104297944 ppf: 1 ppct: 7 formats: fmt: @attributes: type: P tig: atl: Methyl Mercury Exposure at Niigata, Japan: Results of Neurological Examinations of 103 Adults. aug: au: Maruyama, Kimio Yorifuji, Takashi Tsuda, Toshihide Sekikawa, Tomoko Nakadaira, Hiroto Saito, Hisashi affil: Department of Social Welfare and Psychology, Faculty of Nursing, Social Welfare and Psychology, Niigata Seiryo University, 1-5939 Suido-cho, Chuo-ku, Niigata 951-8121, Japan sug: subj: Environmental Exposure Analysis Organic Chemicals Mercury Nervous System Pathology Hair Analysis Human Japan Adult Female Male Neurologic Examination Odds Ratio Descriptive Statistics Logistic Regression Confidence Intervals Data Analysis Software Middle Age Adult: 19-44 years Middle Aged: 45-64 years Female Male ab: Background. Large-scale poisonings caused by methyl mercury (MeHg) have occurred in Japan (Minamata in the 1950s andNiigata in the 1960s) and Iraq (in the 1970s). The current WHO neurological risk standard for adult exposure (hair level: 50 μg/g) was based partly on evidence from Niigata which did not consider any cases who were diagnosed later and/or exposed to low level of MeHg (hair mercury level less than 50 μg/g). Methods. Early in the Niigata epidemic in June 1965 there were two extensive surveys. From these two surveys, we examined 103 adults with hair mercury measurement who consulted two medical institutions. We compared the prevalence and the distribution of neurological signs related to MeHg poisoning between exposure categories. Result. We found 48 subjects with neurological signs related to MeHg poisoning who had hair mercury concentration less than 50 μg/g. Among the neurological signs, sensory disturbance of the bilateral distal extremities was observed more frequently, followed by disequilibrium, hearing impairment, and ataxia, in groups with hair MeHg concentration both below 50 μg/g and over 50 μg/g. Conclusion. The present study suggests the possibility that exposure to MeHg at levels below the current WHO limits could cause neurologic signs, in particular, sensory disturbance. pubtype: Academic Journal doctype: research tables/charts Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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