Studying Interactions by Molecular Dynamics Simulations at High Concentration.

Molecular dynamics simulations have been used to study molecular encounters and recognition. In recent works, simulations using high concentration of interacting molecules have been performed. In this paper, we consider the practical problems for setting up the simulation and to analyse the results...

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Publicado en:Journal of Biomedicine & Biotechnology Vol. 2012; pp. 1 - 10
Autores principales: Fogolari, Federico, Corazza, Alessandra, Toppo, Stefano, Tosatto, Silvio C. E., Viglino, Paolo, Ursini, Fulvio, Esposito, Gennaro
Formato: equations & formulas pictorial research tables/charts Journal Article
Publicado: Wiley-Blackwell 2012
Acceso en línea:Ver este registro en EBSCOhost
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        atl: Studying Interactions by Molecular Dynamics Simulations at High Concentration.
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          Fogolari, Federico
          Corazza, Alessandra
          Toppo, Stefano
          Tosatto, Silvio C. E.
          Viglino, Paolo
          Ursini, Fulvio
          Esposito, Gennaro
        affil: Dipartimento di Scienze Mediche e Biologiche, Università di Udine, Piazzale Kolbe 4, 33100 Udine, Italy; Divisione Biomolecole, Istituto Nazionale Biostrutture e Biosistemi, Viale Medaglie d'Oro 305, 00136 Roma, Italy
      sug:
        subj:
          Computer Simulation Methods
          beta-Globulins Physiology
          Hydrogen Peroxide Physiology
          Oxidoreductases Physiology
          Molecular Biology
          Diffusion
          Algorithms
          Descriptive Statistics
          Models, Statistical
          Data Analysis Software
          Funding Source
      ab: Molecular dynamics simulations have been used to study molecular encounters and recognition. In recent works, simulations using high concentration of interacting molecules have been performed. In this paper, we consider the practical problems for setting up the simulation and to analyse the results of the simulation. The simulation of beta 2-microglobulin association and the simulation of the binding of hydrogen peroxide by glutathione peroxidase are provided as examples.
      pubtype: Academic Journal
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        equations & formulas
        pictorial
        research
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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