Epidemiology of Helicobacter pylori infection in six Latin American countries (SWOG Trial S0701).
Objective: To investigate the potential determinants of Helicobacter pylori infection between adults 21-65 years old.Methods: Data are from the initial screening visit of a randomized clinical trial of three antibiotic regimens to eradicate H. pylori, conducted in seven sites (Santiago-Chile, Túquer...
| Publicado en: | Cancer Causes & Control Vol. 24; no. 2; pp. 209 - 216 |
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| Autores principales: | , , , , , , , , , , , , , , , , , , , |
| Formato: | research Journal Article |
| Publicado: |
Springer Nature
Feb2013
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=104301669&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 104301669 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 09575243 ODX jtl: Cancer Causes & Control issn: 09575243 maglogo: N pubinfo: dt: Feb2013 vid: 24 iid: 2 pid: 237 pub: Springer Nature place: New York, New York artinfo: ui: 104301669 NLM23263777 2011911615 10.1007/s10552-012-0117-5 NLM23263777 PMC3645498 104301669 ppf: 209 ppct: 7 formats: fmt: @attributes: type: P tig: atl: Epidemiology of Helicobacter pylori infection in six Latin American countries (SWOG Trial S0701). aug: au: Porras C Nodora J Sexton R Ferreccio C Jimenez S Dominguez RL Cook P Anderson G Morgan DR Baker LH Greenberg ER Herrero R Porras, Carolina Nodora, Jesse Sexton, Rachael Ferreccio, Catterina Jimenez, Silvia Dominguez, Ricardo L Cook, Paz Anderson, Garnet affil: Proyecto Epidemiológico Guanacaste, Fundación INCIENSA, Torre La Sabana, 300 mts. Oeste del ICE, planta baja frente al Lobby, Sabana Norte, San Jose, Costa Rica sug: subj: Helicobacter Infections Epidemiology Helicobacter Pylori Adult Aged Clinical Trials Female Helicobacter Infections Diagnosis Human Latin America Male Middle Age Multicenter Studies Risk Factors Young Adult Adult: 19-44 years Aged: 65+ years Middle Aged: 45-64 years Female Male ab: Objective: To investigate the potential determinants of Helicobacter pylori infection between adults 21-65 years old.Methods: Data are from the initial screening visit of a randomized clinical trial of three antibiotic regimens to eradicate H. pylori, conducted in seven sites (Santiago-Chile, Túquerres-Colombia, Guanacaste-Costa Rica, Copán-Honduras, Obregón and Tapachula-México, León-Nicaragua). Thousand eight hundred and fifty-nine adults from the general population were screened for H. pylori infection using an urea breath test (UBT) and were interviewed to assess socioeconomic-, demographic-, and symptom-related characteristics. Logistic regression was used to assess the relationship between these characteristics and H. pylori positivity at enrollment.Results: Among the 1,852 eligible participants for whom a conclusive UBT result was obtained, H. pylori prevalence was 79.4 %, ranging from 70.1 to 84.7 % among the seven centers. Prevalence did not differ by sex (female: 78.4, male: 80.9; p = 0.20) or age (p = 0.08). H. pylori positivity increased with increasing number of siblings (p trend <0.0001). Participants with education beyond 12 years were less likely to be UBT-positive (OR 0.4: 0.3-0.6, compared to participants with 0-6 years of schooling) as were those employed outside the home (OR 0.7: 0.6-1.0). Odds of H. pylori infection increased with the presence of certain living conditions during childhood including having lived in a household with an earth floor (OR 1.8: 1.4-2.4), lack of indoor plumbing (OR 1.3: 1.0-1.8) and crowding (OR 1.4: 1.0-1.8, for having more than two persons per bedroom). Regarding current household conditions, living with more than 3 children in the household (OR 1.7: 1.2-2.5) and crowding (OR 1.8: 1.3-2.3) were associated with H. pylori infection.Conclusions: The prevalence of H. pylori in adults was high and differed significantly among the six Latin American countries studied (p < 0.001). Our findings confirm the strong link between poor socioeconomic conditions and H. pylori infection. pubtype: Academic Journal doctype: research Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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