Efficacy of phototherapy devices and outcomes among extremely low birth weight infants: multi-center observational study.

Objective:Evaluate the efficacy of phototherapy (PT) devices and the outcomes of extremely premature infants treated with those devices.Study Design:This substudy of the National Institute of Child Health and Human Development Neonatal Research Network PT trial included 1404 infants treated with a s...

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Published in:Journal of Perinatology Vol. 33; no. 2; pp. 126 - 134
Main Authors: Morris, B H, Tyson, J E, Stevenson, D K, Oh, W, Phelps, D L, O'Shea, T M, McDavid, G E, Van Meurs, K P, Vohr, B R, Grisby, C, Yao, Q, Kandefer, S, Wallace, D, Higgins, R D
Format: research tables/charts Journal Article
Published: Springer Nature Feb2013
Online Access:View this record in EBSCOhost
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        atl: Efficacy of phototherapy devices and outcomes among extremely low birth weight infants: multi-center observational study.
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          Morris, B H
          Tyson, J E
          Stevenson, D K
          Oh, W
          Phelps, D L
          O'Shea, T M
          McDavid, G E
          Van Meurs, K P
          Vohr, B R
          Grisby, C
          Yao, Q
          Kandefer, S
          Wallace, D
          Higgins, R D
        affil: Department of Neonatology, Trinity Mother Frances Health System, Tyler, TX, USA
      sug:
        subj:
          Phototherapy Equipment and Supplies
          Treatment Outcomes
          Infant, Very Low Birth Weight
          Human
          Funding Source
          Multicenter Studies
          Nonexperimental Studies
          Descriptive Statistics
          Intensive Care Units, Neonatal
          Relative Risk
          Poisson Distribution
          Data Analysis Software
          Chi Square Test
          Male
          Female
          Male
          Female
      ab: Objective:Evaluate the efficacy of phototherapy (PT) devices and the outcomes of extremely premature infants treated with those devices.Study Design:This substudy of the National Institute of Child Health and Human Development Neonatal Research Network PT trial included 1404 infants treated with a single type of PT device during the first 24±12 h of treatment. The absolute (primary outcome) and relative decrease in total serum bilirubin (TSB) and other measures were evaluated. For infants treated with one PT type during the 2-week intervention period (n=1223), adjusted outcomes at discharge and 18 to 22 months corrected age were determined.Result:In the first 24 h, the adjusted absolute (mean (±s.d.)) and relative (%) decrease in TSB (mg dl−1) were: light-emitting diodes (LEDs) −2.2 (±3), −22%; Spotlights −1.7 (±2), −19%; Banks −1.3 (±3), −8%; Blankets −0.8 (±3), −1%; (P<0.0002). Some findings at 18 to 22 months differed between groups.Conclusion:LEDs achieved the greatest initial absolute reduction in TSB but were similar to Spots in the other performance measures. Long-term effects of PT devices in extremely premature infants deserve rigorous evaluation.
      pubtype: Academic Journal
      doctype:
        research
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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