Comparison of geometric uncertainties between alpha cradle and thermoplastic ray cast immobilisation in abdominopelvic radiotherapy: a prospective study.

Context: Setup error significantly affects the accuracy of treatment and outcome in high precision radiotherapy. Aims: To determine total, systematic, random error and clinical target volume (CTV) to planning target volume (PTV) margin with alpha cradle (VL) and ray cast (RC) immobilisation in abdom...

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Publicado en:Journal of Radiotherapy in Practice Vol. 11; no. 4; pp. 239 - 249
Autores principales: Saikat Das, Subhashini John, Paul Ravindran, Rajesh Isiah, Rajesh B, Selvamani Backianathan, Rabi Raja Singh
Formato: pictorial research tables/charts randomized controlled trial Journal Article
Publicado: Cambridge University Press Dec2012
Acceso en línea:Ver este registro en EBSCOhost
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      dt: Dec2012
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      pub: Cambridge University Press
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        atl: Comparison of geometric uncertainties between alpha cradle and thermoplastic ray cast immobilisation in abdominopelvic radiotherapy: a prospective study.
      aug:
        au:
          Saikat Das
          Subhashini John
          Paul Ravindran
          Rajesh Isiah
          Rajesh B
          Selvamani Backianathan
          Rabi Raja Singh
        affil: Christian Medical College Vellore, India
      sug:
        subj:
          Abdomen
          Immobilization Equipment and Supplies
          Pelvis
          Radiotherapy Methods
          Aged
          Descriptive Statistics
          Female
          Human
          Male
          Middle Age
          P-Value
          Paired T-Tests
          Randomized Controlled Trials
          Aged: 65+ years
          Middle Aged: 45-64 years
          Female
          Male
      ab: Context: Setup error significantly affects the accuracy of treatment and outcome in high precision radiotherapy. Aims: To determine total, systematic, random error and clinical target volume (CTV) to planning target volume (PTV) margin with alpha cradle (VL) and ray cast (RC) immobilisation in abdominopelvic region. Methods and material: Setup error was compared by using digitally reconstructed radiograph (DRR) as reference image with electronic portal image (EPI) taken during the treatment. Statistical analysis used: The total errors in mediolateral (ML), craniocaudal (CC) and anteroposterior (AP) directions were compared by t-test. For systematic and random errors variance ratio test (F-statistics) was used. Margins were calculated using International Commission of Radiation Units (ICRU), Stroom's and van Herk's formula. Results: A total number of 306 portal images were analysed with 144 images in RC group and 162 images in VL group. For VL, in ML, CC, AP directions systematic errors were, in cm, (0.45, 0.29, 0.41), random errors (0.48, 0.32, 0.58), CTV to PTV margins (1.24, 0.80, 1.25), respectively. For RC, systematic errors were (0.25, 0.37, 0.80), random error (0.46, 0.80, 0.33), CTV to PTV margins (0.82, 1.30, 1.08), respectively. The difference of random error in CC and AP directions were statistically significant. Conclusions: Geometric errors and CTV to PTV margins are different in different directions. For abdomen and pelvis in VL immobilisation, the margin ranged from 8 mm to 12.4 mm and for RC it was 8.2 mm to 13 mm. Therefore, a margin of 10 mm with online correction would be adequate.
      pubtype: Academic Journal
      doctype:
        pictorial
        research
        tables/charts
        randomized controlled trial
        Journal Article
      ougenre: Article
    language: English
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