Novel technology of multimodal ultrasound tomography detects breast lesions.
Objectives: To introduce a new three-dimensional (3D) diagnostic imaging technology, termed "multimodal ultrasonic tomography" (MUT), for the detection of breast cancer without ionising radiation or compression.Methods: MUT performs 3D tomography of the pendulant breast in a water-bath using transmi...
| Publicado en: | European Radiology Vol. 23; no. 3; pp. 673 - 684 |
|---|---|
| Autores principales: | , , , , , , , , , , , , , |
| Formato: | research Journal Article |
| Publicado: |
Springer Nature
Mar2013
|
| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=104311569&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 104311569 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 09387994 NPH jtl: European Radiology issn: 09387994 maglogo: N pubinfo: dt: Mar2013 vid: 23 iid: 3 pid: 237 pub: Springer Nature place: New York, New York artinfo: ui: 104311569 NLM22983317 2011930683 10.1007/s00330-012-2659-z NLM22983317 104311569 ppf: 673 ppct: 11 formats: fmt: @attributes: type: P tig: atl: Novel technology of multimodal ultrasound tomography detects breast lesions. aug: au: Zografos G Koulocheri D Liakou P Sofras M Hadjiagapis S Orme M Marmarelis V Zografos, G Koulocheri, D Liakou, P Sofras, M Hadjiagapis, S Orme, M Marmarelis, V affil: Breast Unit, 1st Department of Propaedeutic Surgery, School of Medicine, University of Athens, Athens, Greece sug: subj: Algorithms Breast Neoplasms Ultrasonography Image Enhancement Methods Image Interpretation, Computer Assisted Methods Subtraction Technique Ultrasonography Methods Adult Aged Aged, 80 and Over Female Human Reproducibility of Results Sensitivity and Specificity Adult: 19-44 years Aged: 65+ years Aged, 80 & over Female ab: Objectives: To introduce a new three-dimensional (3D) diagnostic imaging technology, termed "multimodal ultrasonic tomography" (MUT), for the detection of breast cancer without ionising radiation or compression.Methods: MUT performs 3D tomography of the pendulant breast in a water-bath using transmission ultrasound in a fixed-coordinate system. Specialised electronic hardware and signal processing algorithms are used to construct multimodal images for each coronal slice, corresponding to measurements of refractivity and frequency-dependent attenuation and dispersion. In-plane pixel size is 0.25 mm × 0.25 mm and the inter-slice interval can vary from 1 to 4 mm, depending on clinical requirements. MUT imaging was performed on 25 patients ("off-label" use for research purposes only), presenting lesions with sizes >10 mm. Histopathology of biopsy samples, obtained from all patients, were used to evaluate the MUT outcomes.Results: All lesions (21 malignant and four benign) were clearly identified on the MUT images and correctly classified into benign and malignant based on their respective multimodal information. Malignant lesions generally exhibited higher values of refractivity and frequency-dependent attenuation and dispersion.Conclusion: Initial clinical results confirmed the ability of MUT to detect and differentiate all suspicious lesions with sizes >10 mm discernible in mammograms of 25 female patients. pubtype: Academic Journal doctype: research Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
|---|