Hepatic pathology after Fontan palliation: spectrum of imaging findings.
Background: Patients with congenital heart disease corrected by Fontan palliation have chronic liver congestion that commonly progresses to fibrosis and cirrhosis with resultant complications.Objective: To define the hepatic imaging characteristics associated with Fontan circulation.Materials and Me...
| Publicado en: | Pediatric Radiology Vol. 43; no. 3; pp. 330 - 339 |
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| Autores principales: | , |
| Formato: | research Journal Article |
| Publicado: |
Springer Nature
Mar2013
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=104317584&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 104317584 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 03010449 O03 jtl: Pediatric Radiology issn: 03010449 maglogo: N pubinfo: dt: Mar2013 vid: 43 iid: 3 pid: 237 pub: Springer Nature place: New York, New York artinfo: ui: 104317584 NLM23052733 2012009822 10.1007/s00247-012-2531-y NLM23052733 104317584 ppf: 330 ppct: 9 formats: fmt: @attributes: type: P tig: atl: Hepatic pathology after Fontan palliation: spectrum of imaging findings. aug: au: Wallihan, Daniel B Podberesky, Daniel J affil: Cincinnati Children's Hospital Medical Center, 3333 Burnett Ave., Cincinnati, OH, 45229, USA, daniel.wallihan@cchmc.org. sug: subj: Cardiopulmonary Bypass Adverse Effects Heart Defects, Congenital Surgery Liver Cirrhosis Diagnosis Liver Cirrhosis Etiology Magnetic Resonance Imaging Methods Tomography, X-Ray Computed Methods Adolescence Child Child, Preschool Female Heart Defects, Congenital Complications Heart Defects, Congenital Diagnosis Human Infant Male Middle Age Palliative Care Methods Retrospective Design Treatment Outcomes Young Adult Adolescent: 13-18 years Child: 6-12 years Child, Preschool: 2-5 years Infant: 1-23 months Middle Aged: 45-64 years Female Male ab: Background: Patients with congenital heart disease corrected by Fontan palliation have chronic liver congestion that commonly progresses to fibrosis and cirrhosis with resultant complications.Objective: To define the hepatic imaging characteristics associated with Fontan circulation.Materials and Methods: A retrospective study was performed in patients who underwent Fontan palliation who had CT or MR examinations including the liver. The liver was evaluated for parenchymal morphology, abnormal enhancement, nodules and imaging findings of fibrosis and cirrhosis.Results: MRI or CT examinations including the liver were evaluated in 42 Fontan patients. The most common imaging finding was abnormal parenchymal enhancement, present in 38 patients. Hypervascular nodules were present in 13 patients (31%). Imaging findings of cirrhosis were seen in eight patients (19%). One patient with cirrhosis had a large liver mass, subsequently diagnosed as fibrolamellar hepatocellular carcinoma.Conclusion: A high percentage of patients had imaging abnormalities of the liver, chiefly abnormal parenchymal enhancement, which became more apparent as the duration of the Fontan circulation increased. The hypervascular nodules sometimes present had imaging characteristics most closely resembling those of focal nodular hyperplasia. The underlying fibrosis and eventual development of cirrhosis raise the risk of developing hepatocellular carcinoma. pubtype: Academic Journal doctype: research Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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