Visually Guided Sequential Pulmonary Vein Isolation: Insights into Techniques and Predictors of Acute Success.

Sequential PVI with Laser Balloon. Introduction: Pulmonary vein isolation (PVI) is a challenging procedure most often requiring sophisticated technical aids such as electroanatomical mapping, double transseptal access, and the use of a circular mapping catheter. We sought to develop a PVI strategy s...

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Publicado en:Journal of Cardiovascular Electrophysiology Vol. 23; no. 6; pp. 576 - 583
Autores principales: Schmidt, Boris, Gunawardene, Melanie, Urban, Verena, Kulikoglu, Mehmet, Schulte-Hahn, Britta, Nowak, Bernd, Bordignon, Stefano, Chun, Kr J.
Formato: diagnostic images research tables/charts Journal Article
Publicado: Wiley-Blackwell Jun2012
Acceso en línea:Ver este registro en EBSCOhost
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        atl: Visually Guided Sequential Pulmonary Vein Isolation: Insights into Techniques and Predictors of Acute Success.
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          Schmidt, Boris
          Gunawardene, Melanie
          Urban, Verena
          Kulikoglu, Mehmet
          Schulte-Hahn, Britta
          Nowak, Bernd
          Bordignon, Stefano
          Chun, Kr J.
        affil: Cardioangiologisches Centrum Bethanien, Frankfurt, Germany
      sug:
        subj:
          Pulmonary Veins Surgery
          Catheter Ablation Methods
          Atrial Fibrillation Surgery
          Treatment Outcomes
          Human
          Male
          Female
          Aged
          Middle Age
          Descriptive Statistics
          Parametric Statistics
          Nonparametric Statistics
          One-Way Analysis of Variance
          Post Hoc Analysis
          Funding Source
          Aged: 65+ years
          Middle Aged: 45-64 years
          Male
          Female
      ab: Sequential PVI with Laser Balloon. Introduction: Pulmonary vein isolation (PVI) is a challenging procedure most often requiring sophisticated technical aids such as electroanatomical mapping, double transseptal access, and the use of a circular mapping catheter. We sought to develop a PVI strategy solely based on visual guidance with a single ablation device as well as a single transseptal puncture using the endoscopic ablation system (EAS). Methods and Results: In 35 patients with drug-refractory atrial fibrillation (18 male, mean age: 62 ± 9 years) ablation was performed. PVI was achieved in 96 of 137 PVs (70%) purely by visually guided circular ablation. Predictors of acute isolation were the degree of PV occlusion by EAS as well as the number of catheter repositionings but not total ablation energy or the number of laser applications. Conduction gaps were detected at sites with suboptimal occlusion as well as esophageal temperature elevations. Further EAS ablation resulted in a 98% acute isolation rate. Mean procedure and fluoroscopy times were 154 ± 38 minutes and 16 ± 6 minutes, respectively. Between the first and last 12 cases, a reduction in procedure times (175 ± 48 minutes vs 138 ± 26 minutes; P = 0.05) was observed. One pericardial tamponade and 1 right-sided phrenic nerve palsy occurred. During a median follow-up of 266 days (q-q3: 218-389), 27 of 35 patients (77%) remained free of any tachyarrhythmia recurrence off antiarrhythmic drugs. Conclusions: Sequential PVI based solely on endoscopic visual information with a single device and a single transseptal puncture is feasible. Optimal PV occlusion and few controlled repositionings facilitate PVI. (J Cardiovasc Electrophysiol, Vol. 23, pp. 576-582, June 2012)
      pubtype: Academic Journal
      doctype:
        diagnostic images
        research
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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