Changes in brain transcripts related to Alzheimer's disease in a model of HFE hemochromatosis are not consistent with increased Alzheimer's disease risk.

Iron abnormalities are observed in the brains of Alzheimer's disease (AD) patients, but it is unclear whether common disorders of systemic iron overload such as hemochromatosis alter risks of AD. We used microarrays and real-time reverse transcription-PCR to investigate changes in the brain transcri...

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Publicado en:Journal of Alzheimer's Disease Vol. 28; no. 1; pp. 791 - 804
Autores principales: Johnstone DM, Graham RM, Trinder D, Riveros C, Olynyk JK, Scott RJ, Moscato P, Milward EA, Johnstone, Daniel M, Graham, Ross M, Trinder, Debbie, Riveros, Carlos, Olynyk, John K, Scott, Rodney J, Moscato, Pablo, Milward, Elizabeth A
Formato: research Journal Article
Publicado: Sage Publications Inc. 2012
Acceso en línea:Ver este registro en EBSCOhost