Feature engineering combined with machine learning and rule-based methods for structured information extraction from narrative clinical discharge summaries.

Objective: A system that translates narrative text in the medical domain into structured representation is in great demand. The system performs three sub-tasks: concept extraction, assertion classification, and relation identification.Design: The overall system consists of five steps: (1) pre-proces...

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Publicado en:Journal of the American Medical Informatics Association Vol. 19; no. 5; pp. 824 - 833
Autores principales: Xu, Yan, Hong, Kai, Tsujii, Junichi, Chang, Eric I-Chao
Formato: research Journal Article
Publicado: Oxford University Press / USA Sep2012
Acceso en línea:Ver este registro en EBSCOhost
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      pub: Oxford University Press / USA
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        atl: Feature engineering combined with machine learning and rule-based methods for structured information extraction from narrative clinical discharge summaries.
      aug:
        au:
          Xu, Yan
          Hong, Kai
          Tsujii, Junichi
          Chang, Eric I-Chao
        affil: State Key Laboratory of Software Development Environment, Key Laboratory of Biomechanics and Mechanobiology of the Ministry of Education, Beihang University, Beijing, China.
      sug:
        subj:
          Data Mining Methods
          Electronic Health Records
          Natural Language Processing
          Patient Discharge
          Artificial Intelligence
          Human
          Vocabulary, Controlled
      ab: Objective: A system that translates narrative text in the medical domain into structured representation is in great demand. The system performs three sub-tasks: concept extraction, assertion classification, and relation identification.Design: The overall system consists of five steps: (1) pre-processing sentences, (2) marking noun phrases (NPs) and adjective phrases (APs), (3) extracting concepts that use a dosage-unit dictionary to dynamically switch two models based on Conditional Random Fields (CRF), (4) classifying assertions based on voting of five classifiers, and (5) identifying relations using normalized sentences with a set of effective discriminating features.Measurements: Macro-averaged and micro-averaged precision, recall and F-measure were used to evaluate results.Results: The performance is competitive with the state-of-the-art systems with micro-averaged F-measure of 0.8489 for concept extraction, 0.9392 for assertion classification and 0.7326 for relation identification.Conclusions: The system exploits an array of common features and achieves state-of-the-art performance. Prudent feature engineering sets the foundation of our systems. In concept extraction, we demonstrated that switching models, one of which is especially designed for telegraphic sentences, improved extraction of the treatment concept significantly. In assertion classification, a set of features derived from a rule-based classifier were proven to be effective for the classes such as conditional and possible. These classes would suffer from data scarcity in conventional machine-learning methods. In relation identification, we use two-staged architecture, the second of which applies pairwise classifiers to possible candidate classes. This architecture significantly improves performance.
      pubtype: Academic Journal
      doctype:
        research
        Journal Article
      ougenre: Article
    language: English
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