Preoperative incisional and intraoperative frozen section biopsy techniques have comparable accuracy in the diagnosis of benign intraosseous jaw pathology.
PURPOSE: To compare the accuracy of intraoperative frozen section (FS) and preoperative incisional biopsy (IB) techniques to diagnose benign intraosseous jaw lesions. MATERIALS AND METHODS: This is a retrospective cohort study composed of subjects with benign intraosseous jaw lesions. The predictor...
| Publicado en: | Journal of Oral & Maxillofacial Surgery (02782391) Vol. 70; no. 11; pp. 2566 - 2573 |
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| Autores principales: | , , , , |
| Formato: | research Journal Article |
| Publicado: |
W B Saunders
Nov2012
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=104375599&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 104375599 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 02782391 1YP jtl: Journal of Oral & Maxillofacial Surgery (02782391) issn: 02782391 maglogo: N pubinfo: dt: Nov2012 vid: 70 iid: 11 pid: 1351 pub: W B Saunders place: Philadelphia, Pennsylvania artinfo: ui: 104375599 2011719145 10.1016/j.joms.2011.11.023 NLM22285333 104375599 ppf: 2566 ppct: 7 formats: tig: atl: Preoperative incisional and intraoperative frozen section biopsy techniques have comparable accuracy in the diagnosis of benign intraosseous jaw pathology. aug: au: Guthrie D Peacock ZS Sadow P Dodson TB August M affil: Predoctoral student, Harvard School of Dental Medicine, Boston, MA. Electronic address: guthrie.10@gmail.com. sug: subj: Biopsy Methods Jaw Cysts Pathology Jaw Neoplasms Pathology Adolescence Adult Aged Aged, 80 and Over Child Prospective Studies Female Frozen Sections Human Intraoperative Care Male Middle Age Preoperative Care Retrospective Design Young Adult Adolescent: 13-18 years Adult: 19-44 years Aged: 65+ years Aged, 80 & over Child: 6-12 years Middle Aged: 45-64 years Female Male ab: PURPOSE: To compare the accuracy of intraoperative frozen section (FS) and preoperative incisional biopsy (IB) techniques to diagnose benign intraosseous jaw lesions. MATERIALS AND METHODS: This is a retrospective cohort study composed of subjects with benign intraosseous jaw lesions. The predictor variable was the technique for establishing a preliminary diagnosis of the lesion, preoperative IB or intraoperative FS. The outcome variable was the accuracy of the biopsy technique when compared with the final histologic diagnosis and was classified as concordant or discordant. The comparative diagnostic accuracy of the techniques was assessed with the [chi](2) test. RESULTS: A total of 71 subjects met inclusion criteria. The mean age was 39 years (range, 5 to 85 years), and 58% (41) were male patients. Of the subjects, 20 (28%) underwent IB. In 14 (70%) of these, the results of biopsy agreed with the final diagnosis. 51 (72%) underwent intraoperative FS and in 31 (62%) of these, the results of biopsy agreed with the final diagnosis. The difference in diagnostic accuracy between IB (70%) and FS (61%) was statistically insignificant (P = .48). Sources of biopsy error included sampling error (46%), insufficient epithelial tissue (15%), inflammation (15%), pathologist's experience (8%), and artifact (4%). CONCLUSIONS: Preoperative IB and intraoperative FS provide comparable accuracy of diagnosis in patients with benign intraosseous jaw pathology. Sampling error was the most common reason for discordant results. pubtype: Academic Journal doctype: research Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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