Statistical analysis of high frequency ultrasonic backscattered signals from basal cell carcinomas.

A statistical approach was implemented in the study of histologic characteristics from ex vivo basal cell carcinomas, based on the properties of backscattered acoustic waves, for the purpose of evaluating the method as a diagnostic tool. The study was developed using an ultrasound biomicroscope work...

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Publicado en:Ultrasound in Medicine & Biology Vol. 38; no. 10; pp. 1811 - 1820
Autores principales: Petrella LI, de Azevedo Valle H, Issa PR, Martins CJ, Machado JC, Pereira WC, Petrella, Lorena Itatí, de Azevedo Valle, Heliomar, Issa, Paulo Roberto, Martins, Carlos José, Machado, João Carlos, Pereira, Wagner Coelho A
Formato: research Journal Article
Publicado: Elsevier B.V. Oct2012
Acceso en línea:Ver este registro en EBSCOhost
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      jtl: Ultrasound in Medicine & Biology
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      dt: Oct2012
      vid: 38
      iid: 10
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      pub: Elsevier B.V.
      place: New York, New York
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        104378305
        NLM22920547
        2011735929
        10.1016/j.ultrasmedbio.2012.06.001
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        atl: Statistical analysis of high frequency ultrasonic backscattered signals from basal cell carcinomas.
      aug:
        au:
          Petrella LI
          de Azevedo Valle H
          Issa PR
          Martins CJ
          Machado JC
          Pereira WC
          Petrella, Lorena Itatí
          de Azevedo Valle, Heliomar
          Issa, Paulo Roberto
          Martins, Carlos José
          Machado, João Carlos
          Pereira, Wagner Coelho A
        affil: Laboratory of Ultrasound, National Institute of Metrology, Quality and Technology, Duque de Caxias, RJ, Brazil
      sug:
        subj:
          Carcinoma, Basal Cell Pathology
          Carcinoma, Basal Cell Ultrasonography
          Image Interpretation, Computer Assisted Methods
          Microscopy Methods
          Skin Neoplasms Pathology
          Skin Neoplasms Ultrasonography
          Data Analysis, Statistical
          Human
          Radiation Dosage
          Reproducibility of Results
          Scattering, Radiation
          Sensitivity and Specificity
          Sound
      ab: A statistical approach was implemented in the study of histologic characteristics from ex vivo basal cell carcinomas, based on the properties of backscattered acoustic waves, for the purpose of evaluating the method as a diagnostic tool. The study was developed using an ultrasound biomicroscope working at a frequency of 45 MHz. The parameters examined were signal-to-noise ratio (SNR), and shape parameters from the Weibull (b(W)) and generalized gamma (c(GG) and υ(GG)) probability density functions. Twenty-seven carcinomatous skin samples were obtained from volunteer patients and classified into two groups (BCC1 and BCC2) based on the distribution patterns of their tumor nests; also, seven non-tumoral samples were used for comparative purposes. Significant differences between groups were obtained for all studied parameters. The successful differentiation between some tissue groups suggests its potential use for carcinoma characterization.
      pubtype: Academic Journal
      doctype:
        research
        Journal Article
      ougenre: Article
    language: English
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