Characterisation of urinary stones in the presence of iodinated contrast medium using dual-energy CT: a phantom study.
Objective: To develop a dual-energy CT (DECT) method for differentiating uric acid (UA) from non-UA stones in the presence of iodinated contrast medium.Methods: Thirty UA and 45 non-UA stones were selected after infra-red spectroscopic analysis and independently placed in a 1.5-ml vial, which was fi...
| Publicado en: | European Radiology Vol. 22; no. 12; pp. 2589 - 2597 |
|---|---|
| Autores principales: | , , , , , , , , , , , , , |
| Formato: | research Journal Article |
| Publicado: |
Springer Nature
Dec2012
|
| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=104378920&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 104378920 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 09387994 NPH jtl: European Radiology issn: 09387994 maglogo: N pubinfo: dt: Dec2012 vid: 22 iid: 12 pid: 237 pub: Springer Nature place: New York, New York artinfo: ui: 104378920 83006734 NLM22865225 2011737164 10.1007/s00330-012-2532-0 NLM22865225 PMC3970240 104378920 ppf: 2589 ppct: 8 formats: fmt: – @attributes: type: T – @attributes: type: P tig: atl: Characterisation of urinary stones in the presence of iodinated contrast medium using dual-energy CT: a phantom study. aug: au: Wang J Qu M Duan X Takahashi N Kawashima A Leng S McCollough CH Wang, Jia Qu, Mingliang Duan, Xinhui Takahashi, Naoki Kawashima, Akira Leng, Shuai McCollough, Cynthia H affil: Department of Radiology, Mayo Clinic, 200 First Street SW, Rochester, MN 55905, USA sug: subj: Tomography, X-Ray Computed Methods Urinary Calculi Radiography Contrast Media Diagnostic Use Human Image Processing, Computer Assisted Phantoms, Imaging ROC Curve Sensitivity and Specificity Urinary Calculi Urography Methods ab: Objective: To develop a dual-energy CT (DECT) method for differentiating uric acid (UA) from non-UA stones in the presence of iodinated contrast medium.Methods: Thirty UA and 45 non-UA stones were selected after infra-red spectroscopic analysis and independently placed in a 1.5-ml vial, which was filled first with saline and then with increasing concentrations of iodine. For each condition, tubes were put in a 35-cm water phantom and examined using a dual-source CT system at 100 and 140 kV. Virtual unenhanced images created from CT data sets of the stones in iodine-containing solutions provided position and volume information. This map was used to calculate a CT number ratio to differentiate stone type. A region-growing method was developed to improve the ability to differentiate between UA and non-UA stones with iodinated contrast medium.Results: The sensitivity for detecting UA stones was 100 % for unenhanced images but fell to 18 % with 20 mgI/ml iodine solution and 0 % for higher concentrations. With region growing, the sensitivity for detecting UA stones was increased to 100 %, 82 %, 57 %, 50 % and 21 % for iodine solutions of 20, 40, 60, 80 and 100 mgI/ml.Conclusion: The region-growing method improves differentiation of UA from non-UA stones on contrast-enhanced DECT urograms.Key Points: Computed tomography is widely used to assess renal tract calculi. Dual-energy CT can assess stone composition and provide virtual unenhanced images. However, iodinated contrast medium affects the volume estimation for urinary stones. CTR of stones is altered by the surrounding iodine in CT urograms. The region-growing method improves the identification of uric acid stones. pubtype: Academic Journal doctype: research Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
|---|