Gastric cancer detection using MDCT compared with 2D axial CT: diagnostic accuracy of three different reconstruction techniques.

Purpose: To assess the diagnostic accuracy of different reconstruction techniques using MDCT for gastric cancer detection compared with 2D axial CT. Materials and Methods: During 7 months, we performed CT examinations of 104 consecutive patients with gastric cancer and of a control group composed of...

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Published in:Abdominal Imaging Vol. 37; no. 4; pp. 541 - 549
Main Authors: Kim JH, Eun HW, Hong SS, Kim YJ, Han JK, Choi BI, Kim, Jung Hoon, Eun, Hyo Won, Hong, Seong Sook, Kim, Young Jae, Han, Joon Koo, Choi, Byung Ihn
Format: research Journal Article
Published: Springer Nature Aug2012
Online Access:View this record in EBSCOhost
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      dt: Aug2012
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      pub: Springer Nature
      place: New York, New York
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        atl: Gastric cancer detection using MDCT compared with 2D axial CT: diagnostic accuracy of three different reconstruction techniques.
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          Kim JH
          Eun HW
          Hong SS
          Kim YJ
          Han JK
          Choi BI
          Kim, Jung Hoon
          Eun, Hyo Won
          Hong, Seong Sook
          Kim, Young Jae
          Han, Joon Koo
          Choi, Byung Ihn
        affil: Department of Radiology, Seoul National University College of Medicine, Chongno-gu, Korea
      sug:
        subj:
          Image Processing, Computer Assisted Methods
          Tomography, X-Ray Computed
          Stomach Neoplasms Radiography
          Tomography, X-Ray Computed Methods
          Adult
          Aged
          Early Detection of Cancer
          Female
          Gastroscopy
          Human
          Male
          Middle Age
          Prognosis
          ROC Curve
          Retrospective Design
          Sensitivity and Specificity
          Adult: 19-44 years
          Aged: 65+ years
          Middle Aged: 45-64 years
          Female
          Male
      ab: Purpose: To assess the diagnostic accuracy of different reconstruction techniques using MDCT for gastric cancer detection compared with 2D axial CT. Materials and Methods: During 7 months, we performed CT examinations of 104 consecutive patients with gastric cancer and of a control group composed of 35 patients without gastric disease. All gastric cancer was pathologically proven by endoscopy and surgery. Among 104 patients with gastric cancer, 63 patients had early gastric cancer (EGC). Two radiologists retrospectively and independently interpreted the axial CT and three different reconstruction techniques including multiplanar reformation (MPR), transparent imaging (TI), and virtual gastroscopy (VG), using a commercially available, 3D workstation. They graded the presence or absence of gastric cancer in each image sets using a five-point scale and, if present, they assessed its location. Diagnostic accuracy was compared using the area under the receiver operating characteristic curve (Az) for both gastric cancer and only EGC. Sensitivity and specificity were also calculated for each image technique. The k statistics were used to determine inter-observer agreement. Results: The diagnostic accuracy for overall gastric cancer detection for each of the image sets was as follows: 2D axial CT (Az = 0.858); MPR (Az = 0.879); TI (Az = 0.873); and VG (Az = 0.928). VG had significantly better performance than 2D axial CT (p = 0.016). The sensitivity and specificity were as follows: 76.7% and 82.9% in axial CT; 79.6% and 85.7% in MPR; 91.3% and 80% in TI; and 95.1% and 74.3% in VG. In EGC, the diagnostic performance for its detection was as follows: axial CT (Az = 0.777); MPR (Az = 0.811); TI (Az = 0.825); and VG (Az = 0.896). VG had significantly better performance than both 2D axial CT (P = 0.006) and MRP (P = 0.038). The sensitivity and specificity were as follows: 62.9% and 82.9% in axial CT; 67.7% and 85.7% in MPR; 85.5% and 80% in TI; and 91.9% and 74.3% in VG. The inter-observer agreement showed substantial agreement (κ = 0.67-0.75). Conclusion: Among the different reconstruction techniques, VG accurately detects gastric cancer and is especially useful for EGC compared with 2D axial CT.
      pubtype: Academic Journal
      doctype:
        research
        Journal Article
      ougenre: Article
    language: English
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