Mouse atlas registration with non-tomographic imaging modalities-a pilot study based on simulation.
Purpose: This study investigates methodologies for the estimation of small animal anatomy from non-tomographic modalities, such as planar X-ray projections, optical cameras, and surface scanners. The key goal is to register a digital mouse atlas to a combination of non-tomographic modalities, in ord...
| Publicado en: | Molecular Imaging & Biology Vol. 14; no. 4; pp. 408 - 420 |
|---|---|
| Autores principales: | , , , , , |
| Formato: | research Journal Article |
| Publicado: |
Springer Nature
Aug2012
|
| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=104382894&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 104382894 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 15361632 KJU jtl: Molecular Imaging & Biology issn: 15361632 maglogo: N pubinfo: dt: Aug2012 vid: 14 iid: 4 pid: 237 pub: Springer Nature place: New York, New York artinfo: ui: 104382894 NLM21983855 2011753437 10.1007/s11307-011-0519-x NLM21983855 PMC3340486 104382894 ppf: 408 ppct: 12 formats: fmt: @attributes: type: P tig: atl: Mouse atlas registration with non-tomographic imaging modalities-a pilot study based on simulation. aug: au: Wang H Stout DB Chatziioannou AF Wang, Hongkai Stout, David B Chatziioannou, Arion F affil: Crump Institute of Molecular Imaging, David Geffen School of Medicine, UCLA, Los Angeles, CA, USA sug: subj: Anatomy Computer Simulation Diagnostic Imaging Methods Maps Tomography Methods Animal Studies Mice Phantoms, Imaging Pilot Studies ab: Purpose: This study investigates methodologies for the estimation of small animal anatomy from non-tomographic modalities, such as planar X-ray projections, optical cameras, and surface scanners. The key goal is to register a digital mouse atlas to a combination of non-tomographic modalities, in order to provide organ-level anatomical references of small animals in 3D.Procedures: A 2D/3D registration method was developed to register the 3D atlas to the combination of non-tomographic imaging modalities. Eleven combinations of three non-tomographic imaging modalities were simulated, and the registration accuracy of each combination was evaluated.Results: Comparing the 11 combinations, the top-view X-ray projection combined with the side-view optical camera yielded the best overall registration accuracy of all organs. The use of a surface scanner improved the registration accuracy of skin, spleen, and kidneys.Conclusions: The methodologies and evaluation presented in this study should provide helpful information for designing preclinical atlas-based anatomical data acquisition systems. pubtype: Academic Journal doctype: research Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
|---|