Pediatric liver MR elastography.
Introduction: Many chronic pediatric liver disorders are complicated by the development of fibrosis and ultimately cirrhosis. Although hepatic fibrogenesis progresses along a common pathway irrespective of the specific etiology, fibrosis in pediatric liver diseases has different histopathological pa...
| Publicado en: | Digestive Diseases & Sciences Vol. 57; no. 10; pp. 2713 - 2720 |
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| Autores principales: | , , , , , |
| Formato: | research Journal Article |
| Publicado: |
Springer Nature
Oct2012
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=104383441&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 104383441 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 01632116 1VP jtl: Digestive Diseases & Sciences issn: 01632116 maglogo: N pubinfo: dt: Oct2012 vid: 57 iid: 10 pid: 237 pub: Springer Nature place: New York, New York artinfo: ui: 104383441 104383441 NLM22569825 2011754383 NLM22569825 104383441 ppf: 2713 ppct: 7 formats: tig: atl: Pediatric liver MR elastography. aug: au: Serai SD Towbin AJ Podberesky DJ Serai, Suraj D Towbin, Alexander J Podberesky, Daniel J affil: Department of Radiology, MLC 5031, Cincinnati Children's Hospital and Medical Center, 3333 Burnet Ave., Cincinnati, OH 45229, USA sug: subj: Ultrasonography Equipment and Supplies Ultrasonography Methods Liver Cirrhosis Diagnosis Adolescence Child Child, Preschool Female Human Liver Pathology Liver Cirrhosis Pathology Liver Cirrhosis Radiography Male Sensitivity and Specificity Adolescent: 13-18 years Child: 6-12 years Child, Preschool: 2-5 years Female Male ab: Introduction: Many chronic pediatric liver disorders are complicated by the development of fibrosis and ultimately cirrhosis. Although hepatic fibrogenesis progresses along a common pathway irrespective of the specific etiology, fibrosis in pediatric liver diseases has different histopathological patterns than in adults. In pediatric liver disease, as in adults, management choices may depend upon the stage of fibrosis at diagnosis. With early intervention, the progression of hepatic fibrosis can be slowed or halted, and in some situations, reversed. While liver biopsy is the gold standard for diagnosing and assessing the presence and degree of fibrosis, it has several disadvantages including the potential for sampling error, the risk of complications, the relatively high cost, and general poor acceptance by pediatric patients and their parents. MR elastography (MRE) is a relatively new imaging technique with the potential for allowing a safe, rapid, cost-effective, and non-invasive evaluation of a wide variety of hepatic diseases by quantitatively evaluating the stiffness of the liver parenchyma. The purpose of this article is to present our initial clinical experience and illustrate our modified technique for the application of liver MRE in pediatric patients at our medical center.Methods and Materials: Pediatric MRE techniques were developed and applied to over 45 patients scanned with our new protocol.Conclusion: Liver MRE is a safe, non-invasive method for assessing hepatic fibrosis in pediatric patients. pubtype: Academic Journal doctype: research Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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