Conditional Gata2 inactivation results in HSC loss and lymphatic mispatterning.

The transcription factor GATA-2 plays vital roles in quite diverse developmental programs, including hematopoietic stem cell (HSC) survival and proliferation. We previously identified a vascular endothelial (VE) enhancer that regulates GATA-2 activity in pan-endothelial cells. To more thoroughly def...

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Publicado en:	Journal of Clinical Investigation Vol. 122; no. 10; pp. 3705 - 3718
Autores principales:	Lim KC, Hosoya T, Brandt W, Ku CJ, Hosoya-Ohmura S, Camper SA, Yamamoto M, Engel JD, Lim, Kim-Chew, Hosoya, Tomonori, Brandt, William, Ku, Chia-Jui, Hosoya-Ohmura, Sakie, Camper, Sally A, Yamamoto, Masayuki, Engel, James Douglas
Formato:	research Journal Article
Publicado:	American Society for Clinical Investigation Oct2012
Acceso en línea:	Ver este registro en EBSCOhost