Recognition of medication information from discharge summaries using ensembles of classifiers.

Background: Extraction of clinical information such as medications or problems from clinical text is an important task of clinical natural language processing (NLP). Rule-based methods are often used in clinical NLP systems because they are easy to adapt and customize. Recently, supervised machine l...

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Publicado en:BMC Medical Informatics & Decision Making Vol. 12; no. 1; pp. 36 - 37
Autores principales: Doan, Son, Collier, Nigel, Xu, Hua, Duy, Pham Hoang, Phuong, Tu Minh, Pham, Hoang Duy, Tu, Minh Phuong
Formato: research Journal Article
Publicado: BioMed Central 2012
Acceso en línea:Ver este registro en EBSCOhost
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        atl: Recognition of medication information from discharge summaries using ensembles of classifiers.
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          Doan, Son
          Collier, Nigel
          Xu, Hua
          Duy, Pham Hoang
          Phuong, Tu Minh
          Pham, Hoang Duy
          Tu, Minh Phuong
        affil: National Institute of Informatics, Hitotsubashi, Chiyoda, Tokyo, Japan. sondoan@gmail.com.
      sug:
        subj:
          Information Retrieval Methods
          Medication Systems
          Natural Language Processing
          Patient Discharge
          Information Science
          Algorithms
          Artificial Intelligence
          Decision Support Techniques
          Female
          Human
          Management
          Male
          Drugs
          Reproducibility of Results
          Semantics
          Software Design
          Female
          Male
      ab: Background: Extraction of clinical information such as medications or problems from clinical text is an important task of clinical natural language processing (NLP). Rule-based methods are often used in clinical NLP systems because they are easy to adapt and customize. Recently, supervised machine learning methods have proven to be effective in clinical NLP as well. However, combining different classifiers to further improve the performance of clinical entity recognition systems has not been investigated extensively. Combining classifiers into an ensemble classifier presents both challenges and opportunities to improve performance in such NLP tasks.Methods: We investigated ensemble classifiers that used different voting strategies to combine outputs from three individual classifiers: a rule-based system, a support vector machine (SVM) based system, and a conditional random field (CRF) based system. Three voting methods were proposed and evaluated using the annotated data sets from the 2009 i2b2 NLP challenge: simple majority, local SVM-based voting, and local CRF-based voting.Results: Evaluation on 268 manually annotated discharge summaries from the i2b2 challenge showed that the local CRF-based voting method achieved the best F-score of 90.84% (94.11% Precision, 87.81% Recall) for 10-fold cross-validation. We then compared our systems with the first-ranked system in the challenge by using the same training and test sets. Our system based on majority voting achieved a better F-score of 89.65% (93.91% Precision, 85.76% Recall) than the previously reported F-score of 89.19% (93.78% Precision, 85.03% Recall) by the first-ranked system in the challenge.Conclusions: Our experimental results using the 2009 i2b2 challenge datasets showed that ensemble classifiers that combine individual classifiers into a voting system could achieve better performance than a single classifier in recognizing medication information from clinical text. It suggests that simple strategies that can be easily implemented such as majority voting could have the potential to significantly improve clinical entity recognition.
      pubtype: Academic Journal
      doctype:
        research
        Journal Article
      ougenre: Article
    language: English
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