Clinical software development for the Web: lessons learned from the BOADICEA project.

Background: In the past 20 years, society has witnessed the following landmark scientific advances: (i) the sequencing of the human genome, (ii) the distribution of software by the open source movement, and (iii) the invention of the World Wide Web. Together, these advances have provided a new impet...

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Publicado en:BMC Medical Informatics & Decision Making Vol. 12; no. 1; pp. 30 - 31
Autores principales: Cunningham, Alex P, Antoniou, Antonis C, Easton, Douglas F
Formato: research Journal Article
Publicado: BioMed Central 2012
Acceso en línea:Ver este registro en EBSCOhost
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      pub: BioMed Central
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        atl: Clinical software development for the Web: lessons learned from the BOADICEA project.
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          Cunningham, Alex P
          Antoniou, Antonis C
          Easton, Douglas F
        affil: Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Strangeways Research Laboratory, Worts Causeway, Cambridge CB1 8RN, UK. alex@srl.cam.ac.uk.
      sug:
        subj:
          Breast Neoplasms
          Decision Support Systems, Clinical Administration
          Internet
          Ovarian Neoplasms
          Software Design
          Algorithms
          Proteins
          Breast Neoplasms Prevention and Control
          Computer Simulation
          Decision Support Systems, Clinical Standards
          Equipment Failure
          Equipment Failure Standards
          Female
          Disease Susceptibility
          Human
          Models, Biological
          Mutation
          Ovarian Neoplasms Prevention and Control
          Pilot Studies
          Risk Assessment Methods
          Risk Assessment Standards
          Female
      ab: Background: In the past 20 years, society has witnessed the following landmark scientific advances: (i) the sequencing of the human genome, (ii) the distribution of software by the open source movement, and (iii) the invention of the World Wide Web. Together, these advances have provided a new impetus for clinical software development: developers now translate the products of human genomic research into clinical software tools; they use open-source programs to build them; and they use the Web to deliver them. Whilst this open-source component-based approach has undoubtedly made clinical software development easier, clinical software projects are still hampered by problems that traditionally accompany the software process. This study describes the development of the BOADICEA Web Application, a computer program used by clinical geneticists to assess risks to patients with a family history of breast and ovarian cancer. The key challenge of the BOADICEA Web Application project was to deliver a program that was safe, secure and easy for healthcare professionals to use. We focus on the software process, problems faced, and lessons learned. Our key objectives are: (i) to highlight key clinical software development issues; (ii) to demonstrate how software engineering tools and techniques can facilitate clinical software development for the benefit of individuals who lack software engineering expertise; and (iii) to provide a clinical software development case report that can be used as a basis for discussion at the start of future projects.Results: We developed the BOADICEA Web Application using an evolutionary software process. Our approach to Web implementation was conservative and we used conventional software engineering tools and techniques. The principal software development activities were: requirements, design, implementation, testing, documentation and maintenance. The BOADICEA Web Application has now been widely adopted by clinical geneticists and researchers. BOADICEA Web Application version 1 was released for general use in November 2007. By May 2010, we had > 1200 registered users based in the UK, USA, Canada, South America, Europe, Africa, Middle East, SE Asia, Australia and New Zealand.Conclusions: We found that an evolutionary software process was effective when we developed the BOADICEA Web Application. The key clinical software development issues identified during the BOADICEA Web Application project were: software reliability, Web security, clinical data protection and user feedback.
      pubtype: Academic Journal
      doctype:
        research
        Journal Article
      ougenre: Article
    language: English
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