The impact of chemotherapy-related nausea on patients' nutritional status, psychological distress and quality of life.
Purpose: Nausea is a troublesome and distressing symptom for patients receiving chemotherapy. While vomiting is well controlled with current antiemetics, nausea is a more difficult symptom to manage. The aim of this study was to assess the impact of nausea on nutritional status, quality of life and...
| Publicado en: | Supportive Care in Cancer Vol. 21; no. 1; pp. 59 - 67 |
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| Autores principales: | , , , , , , , |
| Formato: | research Journal Article |
| Publicado: |
Springer Nature
Jan2013
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=104401237&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 104401237 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 09414355 O1J jtl: Supportive Care in Cancer issn: 09414355 maglogo: N pubinfo: dt: Jan2013 vid: 21 iid: 1 pid: 237 pub: Springer Nature place: New York, New York artinfo: ui: 104401237 NLM22610269 2011799416 10.1007/s00520-012-1493-9 NLM22610269 104401237 ppf: 59 ppct: 8 formats: fmt: @attributes: type: P tig: atl: The impact of chemotherapy-related nausea on patients' nutritional status, psychological distress and quality of life. aug: au: Farrell C Brearley SG Pilling M Molassiotis A Farrell, Carole Brearley, Sarah G Pilling, Mark Molassiotis, Alex affil: Christie NHS Foundation Trust, Manchester, UK sug: subj: Antineoplastic Agents Adverse Effects Nausea Chemically Induced Neoplasms Drug Therapy Nutritional Status Quality of Life Stress, Psychological Etiology Activities of Daily Living Adult Aged Anthracyclines Adverse Effects Anxiety Etiology Depression Etiology Female Great Britain Human Male Middle Age Nausea Psychosocial Factors Neoplasms Complications Prospective Studies Psychological Tests Scales Adult: 19-44 years Aged: 65+ years Middle Aged: 45-64 years Female Male ab: Purpose: Nausea is a troublesome and distressing symptom for patients receiving chemotherapy. While vomiting is well controlled with current antiemetics, nausea is a more difficult symptom to manage. The aim of this study was to assess the impact of nausea on nutritional status, quality of life and psychological distress.Methods: This was a prospective observational study over two cycles of chemotherapy. Patients completed the Multinational Association of Supportive Care in Cancer Antiemesis Tool, a measure of nutritional status (Patient-Generated Subjective Global Assessment), the Functional Assessment of Cancer Therapy-General (FACT-G) quality of life scale and the Hospital Anxiety and Depression Scale at the end of each chemotherapy cycle (around day 10 post-chemotherapy).Results: The sample consisted of 104 patients, primarily female, receiving anthracycline-based chemotherapy. While vomiting was minimal (5.2-14.6 % of the patients), high levels of nausea were observed (55.2-72.9 %), and severe nausea (>6 on a 0-10 scale) was reported by 20.5-29.2 % of the participants. Severe nausea had a borderline significant impact in relation to physical functioning (p = 0.025) and a significant impact on nutritional status (severe acute nausea, p = 0.003; severe delayed nausea, p = 0.017). Clinically meaningful changes were observed in relation to the FACT-G total score.Conclusion: Chemotherapy-induced nausea does have an impact on nutritional status and physical functioning and can impair anxiety and quality of life. As a key symptom associated with other symptoms, it is imperative that greater attention is given to managing treatment-related nausea through innovative non-pharmacological and nutritional interventions. pubtype: Academic Journal doctype: research Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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