Hypertensive heart disease: MR tissue phase mapping reveals altered left ventricular rotation and regional myocardial long-axis velocities.
Objectives: The aim of this study was the evaluation of left ventricular (LV) segmental 3D velocities in patients with hypertensive heart disease using magnetic resonance (MR) tissue phase mapping (TPM).Methods: LV radial, long-axis and rotational myocardial velocities were assessed by TPM in patien...
| Publicado en: | European Radiology Vol. 23; no. 2; pp. 339 - 348 |
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| Autores principales: | , , , , , , , , , , , |
| Formato: | research Journal Article |
| Publicado: |
Springer Nature
Feb2013
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=104413599&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 104413599 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 09387994 NPH jtl: European Radiology issn: 09387994 maglogo: N pubinfo: dt: Feb2013 vid: 23 iid: 2 pid: 237 pub: Springer Nature place: New York, New York artinfo: ui: 104413599 NLM22886534 2011893880 10.1007/s00330-012-2613-0 NLM22886534 104413599 ppf: 339 ppct: 9 formats: fmt: @attributes: type: P tig: atl: Hypertensive heart disease: MR tissue phase mapping reveals altered left ventricular rotation and regional myocardial long-axis velocities. aug: au: Foell D Jung B Germann E Staehle F Bode C Markl M Foell, D Jung, B Germann, E Staehle, F Bode, C Markl, M affil: Heart Center Freiburg University, Cardiology and Angiology I, Albert-Ludwigs-University Freiburg, Hugstetter Strasse 55, 79106 Freiburg, Germany sug: subj: Hypertension Complications Hypertrophy, Left Ventricular Complications Hypertrophy, Left Ventricular Diagnosis Diagnostic Imaging Magnetic Resonance Imaging Methods Information Science Adult Aged Case Control Studies Disease Progression Female Human Hypertension Diagnosis Male Middle Age Myocardial Contraction Physiology Reference Values Risk Assessment Rotation Sensitivity and Specificity Severity of Illness Indices Adult: 19-44 years Aged: 65+ years Middle Aged: 45-64 years Female Male ab: Objectives: The aim of this study was the evaluation of left ventricular (LV) segmental 3D velocities in patients with hypertensive heart disease using magnetic resonance (MR) tissue phase mapping (TPM).Methods: LV radial, long-axis and rotational myocardial velocities were assessed by TPM in patients with LV hypertrophy and preserved EF (n = 18, age = 53 ± 12 years) and volunteers (n = 20, age = 51 ± 4 years). Systolic and diastolic peak and time-to-peak velocities were mapped onto a 16-segment LV model. 3D myocardial motion was displayed on an extended visualisation model. Correlation coefficients were calculated to investigate differences in regional dynamics.Results: Patients revealed diastolic dysfunction as expressed by decreased peak long-axis velocities in all (except apical) segments (basal, P ≤ 0.01; two midventricular segments, P = 0.02, P = 0.03). During systole, hypertrophy was associated with heterogeneous behaviour for long-axis velocities including an increase in anteroseptal apical and midventricular regions (P = 0.001), a reduction in mid-inferior segments (P = 0.03) and enhanced septal velocities (P < 0.05). Segmental correlation analysis revealed altered dynamics of LV base rotation and increased dyssynchrony of lateral long-axis motion.Conclusions: Patients with hypertensive heart disease demonstrated alterations in systolic long-axis motion, basal rotation and dyssynchrony. Longitudinal studies are needed to investigate the value of regional wall motion abnormalities regarding disease progression and outcome. pubtype: Academic Journal doctype: research Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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