Association of Between Heavy Metal and Trace Element Levels in Blood and Cervical Mucus with Female Infertility.

Objective: Infertility affects 10-15% of couples during the reproductive period. Ovulatory disorders are more common in younger women whereas unexplained infertility occurs more commonly in older women. Recently, many environmental agents, such as cigarettes, alcohol, heat, electromagnetic energy an...

Descripción completa

Detalles Bibliográficos
Publicado en:Turkiye Klinikleri Journal of Medical Sciences Vol. 32; no. 4; pp. 1032 - 1039
Autores principales: Ilgin, Halil, Hassa, Hikmet, Karatas, Ahmet, Kahraman, Salih, Ilgin, Bade
Formato: research tables/charts Journal Article
Publicado: Turkiye Klinikleri Aug2012
Acceso en línea:Ver este registro en EBSCOhost
fields @attributes:
  recordID: 1
pdfLink:
plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=104415891&site=ehost-live
header:
  @attributes:
    shortDbName: ccm
    uiTerm: 104415891
    longDbName: CINAHL Complete
    uiTag: AN
  controlInfo:
    bkinfo:
    dissinfo:
    jinfo:
      jid:
        13000292
        1VOP
      jtl: Turkiye Klinikleri Journal of Medical Sciences
      issn: 13000292
      maglogo: N
    pubinfo:
      dt: Aug2012
      vid: 32
      iid: 4
      pid: 67298
      pub: Turkiye Klinikleri
    artinfo:
      ui:
        104415891
        2011681431
        10.5336/medsci.2011-26725
        104415891
      ppf: 1032
      ppct: 7
      formats:
        fmt:
          @attributes:
            type: P
      tig:
        atl: Association of Between Heavy Metal and Trace Element Levels in Blood and Cervical Mucus with Female Infertility.
      aug:
        au:
          Ilgin, Halil
          Hassa, Hikmet
          Karatas, Ahmet
          Kahraman, Salih
          Ilgin, Bade
        affil: Clinic of Obstetrics and Gynecology, Bahçe State Hospital, Osmaniye
      sug:
        subj:
          Cervix
          Infertility Risk Factors
          Metals, Heavy Analysis
          Mucus
          Trace Elements Analysis
          Adult
          Cadmium Blood
          Case Control Studies
          Copper Blood
          Data Analysis Software
          Descriptive Statistics
          Female
          Fisher's Exact Test
          Human
          Kruskal-Wallis Test
          Mann-Whitney U Test
          One-Way Analysis of Variance
          Pearson's Correlation Coefficient
          Post Hoc Analysis
          T-Tests
          Zinc Blood
          Adult: 19-44 years
          Female
      ab: Objective: Infertility affects 10-15% of couples during the reproductive period. Ovulatory disorders are more common in younger women whereas unexplained infertility occurs more commonly in older women. Recently, many environmental agents, such as cigarettes, alcohol, heat, electromagnetic energy and radiation have been shown to have negative effects on the reproductive system. Environmental factors and exposure to heavy metals change fertility patterns in adults by affecting germ cell maturation, fertilization and the endocrine system. We aimed to investigate the effect of trace elements and heavy metals in blood and cervical mucus on female infertility. Material and Methods: Study was performed with 50 women: Infertile (n=35) and controls (n=15). Blood and cervical mucus samples were collected to measure Zn, Cu, Cd, and Pb levels. Results: Mean blood plasma and cervical mucus Zn, Cd, and Cu levels in the infertile group were significantly lower than those in the control group. Whole blood Pb level was higher in the infertile group compared to the control group. Although blood Cd level tended to be higher in smokers and cervical mucus Cd level tended to be lower in controls, neither of these difference were statistically significant. Conclusion: Lower levels of plasma and cervical mucus Zn and Cu were thought to result from higher levels of Cd and Pb in blood and cervical mucus. Abnormal levels of heavy metals in blood and cervical mucus may have adverse effects on the female reproductive function.
      pubtype: Academic Journal
      doctype:
        research
        tables/charts
        Journal Article
      ougenre: Article
    language: Turkish
    refInfo:
    holdings:
      @attributes:
        islocal: N