| Sumario: | Gastrointestinal complications of brucellosis are randomly reported, ascites and cholestasis being particularly rare. A 25-year-old female patient with a history of fever, weakness, jaundice, nausea and sweating was admitted to our clinic. The physical examination revealed a temperature of 39.3°C, hepatosplenomegaly and moderate free ascites in the abdomen. Initial laboratory investigation revealed mild anemia, biochemical findings of cholestasis, hypoalbuminemia, elevated serum CA 125 level, increased lymphocyte count in ascidic fluid and low (0.9 g) serum-ascites albumin gradient. After comprehensive evaluation, Brucella melitensis induced ascites, intrahepatic cholestasis and elevated serum CA 125 level were detected. We observed complete clinical and laboratory improvement at the end of anti-brucellosis treatment.
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