Detection of Microcalcification Clusters Using Hessian Matrix and Foveal Segmentation Method on Multiscale Analysis in Digital Mammograms.

Mammography is the most efficient technique for detecting and diagnosing breast cancer. Clusters of microcalcifications have been mainly targeted as a reliable early sign of breast cancer and their earliest detection is essential to reduce the probability of mortality rate. Since the size of microca...

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Publicado en:Journal of Digital Imaging Vol. 25; no. 5; pp. 607 - 620
Autores principales: Thangaraju, Balakumaran, Vennila, Ila, Chinnasamy, Gowrishankar
Formato: diagnostic images equations & formulas research tables/charts Journal Article
Publicado: Springer Nature Oct2012
Acceso en línea:Ver este registro en EBSCOhost
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      dt: Oct2012
      vid: 25
      iid: 5
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      pub: Springer Nature
      place: New York, New York
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        atl: Detection of Microcalcification Clusters Using Hessian Matrix and Foveal Segmentation Method on Multiscale Analysis in Digital Mammograms.
      aug:
        au:
          Thangaraju, Balakumaran
          Vennila, Ila
          Chinnasamy, Gowrishankar
        affil: Department of Electronics and Communication Engineering, Coimbatore Institute of Technology, Coimbatore India
      sug:
        subj:
          Mammography
          Breast Neoplasms Radiography
          Breast Neoplasms Diagnosis
          Diagnosis, Computer Assisted
          Calcinosis Diagnosis
          Radiographic Image Interpretation, Computer-Assisted
          Algorithms
          Radiography, Computed
          Evaluation Research
          ROC Curve
          Human
      ab: Mammography is the most efficient technique for detecting and diagnosing breast cancer. Clusters of microcalcifications have been mainly targeted as a reliable early sign of breast cancer and their earliest detection is essential to reduce the probability of mortality rate. Since the size of microcalcifications is very tiny and may be overlooked by the observing radiologist, we have developed a Computer Aided Diagnosis system for automatic and accurate cluster detection. A three-phased novel approach is presented in this paper. Firstly, regions of interest that corresponds to microcalcifications are identified. This can be achieved by analyzing the bandpass coefficients of the mammogram image. The suspicious regions are passed to the second phase, in which the nodular structured microcalcifications are detected based on eigenvalues of second order partial derivatives of the image and microcalcification pixels are segmented out by exploiting the foveal segmentation in multiscale analysis. Finally, by combining the responses coming out from the second order partial derivatives and the foveal method, potential microcalcifications are detected. The detection performance of the proposed method has been evaluated by using 370 mammograms. The detection method has a TP ratio of 97.76 % with 0.68 false positives per image. We have examined the performance of our computerized scheme using free-response operating characteristics curve.
      pubtype: Academic Journal
      doctype:
        diagnostic images
        equations & formulas
        research
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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