The Relationship Between Skeletal Muscle Oxygenation and Systemic Oxygen Uptake During Exercise in Subjects With COPD: A Preliminary Study.
BACKGROUND: Muscle oxygenation correlates with systemic oxygen uptake (v̇O2 ) in normal subjects; however, whether this relationship exists in COPD patients remains unclear. The purpose of this study was to investigate the influence of skeletal muscle oxygenation on v̇O2during exercise in patients w...
| Publicado en: | Respiratory Care Vol. 57; no. 10; pp. 1602 - 1611 |
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| Autores principales: | , , , , , , , |
| Formato: | equations & formulas research tables/charts Journal Article |
| Publicado: |
Mary Ann Liebert, Inc.
Oct2012
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=104421456&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 104421456 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 00201324 4GG jtl: Respiratory Care issn: 00201324 maglogo: N pubinfo: dt: Oct2012 vid: 57 iid: 10 pid: 1365 pub: Mary Ann Liebert, Inc. place: New Rochelle, New York artinfo: ui: 104421456 82033869 10.4187/respcare.01602 NLM22417907 104421456 ppf: 1602 ppct: 9 formats: fmt: @attributes: type: P tig: atl: The Relationship Between Skeletal Muscle Oxygenation and Systemic Oxygen Uptake During Exercise in Subjects With COPD: A Preliminary Study. aug: au: Kazuyuki Tabira Jun Horie Hiromasa Fujii Toshio Aida Ken-ichi Ito Takahiko Fukumoto Hidetaka Imagita Hideki Ishihara affil: Department of Physical Therapy, Faculty of Health Science, Kio University, Koryo, Japan sug: subj: Pulmonary Disease, Chronic Obstructive Pathology Oxygen Consumption Muscle, Skeletal Exercise Human Ergometry Pulmonary Gas Exchange Oxygen Saturation Pearson's Correlation Coefficient Heart Rate Male Forced Expiratory Volume Vital Capacity Descriptive Statistics Middle Age Aged Aged, 80 and Over Data Analysis Software Exercise Test Funding Source Middle Aged: 45-64 years Aged: 65+ years Aged, 80 & over Male ab: BACKGROUND: Muscle oxygenation correlates with systemic oxygen uptake (v̇O2 ) in normal subjects; however, whether this relationship exists in COPD patients remains unclear. The purpose of this study was to investigate the influence of skeletal muscle oxygenation on v̇O2during exercise in patients with COPD. METHODS: Eight subjects performed an incremental cycle ergometer exercise test. We measured ventilation and pulmonary gas exchange with a metabolic measurement system. We also continuously monitored SpO2, and measured tissue oxygen saturation (StO2 ) in the vastus lateralis with continuous-wave near-infrared spectroscopy. We calculated the muscle oxygen extraction rate (MOER) based on SpO2 and StO2. In addition, we calculated Pearson correlation coefficients to examine the relationships between the v̇O2obtained during exercise testing and the mean values of SpO2 , StO2, heart rate (HR), and MOER for each 30-second interval of the tests. Finally, we analyzed the relationships between the peak v̇O2and the slopes of HR/ v̇O2 , SpO2 / v̇O2, StO2 /̇O2, and MOER/ v̇O2 . RESULTS: With the increasing exercise intensity, many subjects showed a gradual decrease in StO2 and SpO2, but a gradual increase in HR and MOER. ̇O2was negatively correlated with StO2 and SpO2 , and was positively correlated with HR and MOER. However, peak ̇O2was not correlated with any of the slopes. CONCLUSIONS: ̇O2is highly influenced by oxygen utilization in exercising muscles, as well as by blood oxygenation levels and cardiac function. However, the impact of skeletal muscle utilization during exercise on peak ̇O2 varied greatly among the subjects. pubtype: Academic Journal doctype: equations & formulas research tables/charts Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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