Skull Stripping of Neonatal Brain MRI: Using Prior Shape Information with Graph Cuts.

In this paper, we propose a novel technique for skull stripping of infant (neonatal) brain magnetic resonance images using prior shape information within a graph cut framework. Skull stripping plays an important role in brain image analysis and is a major challenge for neonatal brain images. Popular...

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Detalles Bibliográficos
Publicado en:Journal of Digital Imaging Vol. 25; no. 6; pp. 802 - 815
Autor principal: Mahapatra, Dwarikanath
Formato: diagnostic images research tables/charts Journal Article
Publicado: Springer Nature Dec2012
Acceso en línea:Ver este registro en EBSCOhost
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      pub: Springer Nature
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        atl: Skull Stripping of Neonatal Brain MRI: Using Prior Shape Information with Graph Cuts.
      aug:
        au: Mahapatra, Dwarikanath
        affil: Department of Computer Science, Swiss Federal Institute of Technology (ETH), Room CAB F 61.1, Universitätstrasse 6 8092 Zurich Switzerland
      sug:
        subj:
          Skull Radiography
          Brain Radiography
          Radiographic Image Enhancement Methods
          Algorithms
          Automation
          False Positive Results
          Comparative Studies
          Sensitivity and Specificity
          T-Tests
          P-Value
          Infant, Newborn
          Human
          Infant, Newborn: birth-1 month
      ab: In this paper, we propose a novel technique for skull stripping of infant (neonatal) brain magnetic resonance images using prior shape information within a graph cut framework. Skull stripping plays an important role in brain image analysis and is a major challenge for neonatal brain images. Popular methods like the brain surface extractor (BSE) and brain extraction tool (BET) do not produce satisfactory results for neonatal images due to poor tissue contrast, weak boundaries between brain and non-brain regions, and low spatial resolution. Inclusion of prior shape information helps in accurate identification of brain and non-brain tissues. Prior shape information is obtained from a set of labeled training images. The probability of a pixel belonging to the brain is obtained from the prior shape mask and included in the penalty term of the cost function. An extra smoothness term is based on gradient information that helps identify the weak boundaries between the brain and non-brain region. Experimental results on real neonatal brain images show that compared to BET, BSE, and other methods, our method achieves superior segmentation performance for neonatal brain images and comparable performance for adult brain images.
      pubtype: Academic Journal
      doctype:
        diagnostic images
        research
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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