Use and usefulness of adrenal core biopsies without FNA or on-site evaluation of adequacy: a study of 204 cases for a 12-year period.
While several studies have assessed the efficacy of adrenal fine-needle aspiration, there are few data regarding adrenal tissue core biopsies. We performed a retrospective study, for a 12-year period, of 204 percutaneous adrenal core biopsy specimens. A core was the only specimen obtained, and on-si...
| Publicado en: | American Journal of Clinical Pathology Vol. 137; no. 1; pp. 124 - 132 |
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| Autores principales: | , , |
| Formato: | research Journal Article |
| Publicado: |
Oxford University Press / USA
Jan2012
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=104439659&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 104439659 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 00029173 2RW jtl: American Journal of Clinical Pathology issn: 00029173 maglogo: N pubinfo: dt: Jan2012 vid: 137 iid: 1 pid: 10398 pub: Oxford University Press / USA artinfo: ui: 104439659 104439659 2011750262 NLM22180486 104439659 ppf: 124 ppct: 8 formats: tig: atl: Use and usefulness of adrenal core biopsies without FNA or on-site evaluation of adequacy: a study of 204 cases for a 12-year period. aug: au: Villelli NW Jayanti MK Zynger DL affil: Department of Pathology, The Ohio State University Medical Center, Columbus, OH 43210, USA. sug: subj: Adrenal Gland Neoplasms Diagnosis Adrenal Glands Pathology Biopsy, Needle Methods Lung Neoplasms Diagnosis Adrenal Gland Neoplasms Metabolism Adrenal Gland Neoplasms Adult Aged Aged, 80 and Over Female Human Immunohistochemistry Lung Neoplasms Metabolism Male Middle Age Predictive Value of Tests Retrospective Design Tumor Markers, Biological Metabolism Young Adult Adult: 19-44 years Aged: 65+ years Aged, 80 & over Middle Aged: 45-64 years Female Male ab: While several studies have assessed the efficacy of adrenal fine-needle aspiration, there are few data regarding adrenal tissue core biopsies. We performed a retrospective study, for a 12-year period, of 204 percutaneous adrenal core biopsy specimens. A core was the only specimen obtained, and on-site evaluation was not used. About half of the cases (104/204) were diagnosed as metastatic carcinoma, with lung as the most common origin (78/204). A specificity and sensitivity of 100% for benign vs malignant was calculated, with a specificity of 88% and sensitivity of 86% for specific diagnoses. Diagnostic and sampling errors were identified. False-negatives were limited to biopsies using 20-gauge needles. Cases with a clinical history provided had specific diagnoses made at a slightly higher frequency compared with cases without an available history. Immunohistochemical workup was performed in more than half of the cases; specific diagnoses were made more frequently than in cases without immunostains. pubtype: Academic Journal doctype: research Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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