Quantitative evaluation of the tibial tunnel after anterior cruciate ligament reconstruction using diffusion weighted and dynamic contrast enhanced MRI: a follow-up feasibility study.

Objective: The aim of the study was to evaluate the feasibility of two quantitative MRI methods: diffusion weighted imaging (DWI) and dynamic contrast enhanced imaging (DCEI), for follow-up assessment of the tibial tunnel after reconstruction of the anterior cruciate ligament (ACL).Materials and Met...

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Published in:Skeletal Radiology Vol. 41; no. 5; pp. 569 - 575
Main Authors: Rupreht M, Jevtic V, Sersa I, Vogrin M, Seruga T, Jevsek M, Rupreht, Mitja, Jevtič, Vladimir, Serša, Igor, Vogrin, Matjaž, Seruga, Tomaž, Jevšek, Marko
Format: research Journal Article
Published: Springer Nature May2012
Online Access:View this record in EBSCOhost
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      dt: May2012
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      pub: Springer Nature
      place: New York, New York
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        NLM21879337
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        10.1007/s00256-011-1256-6
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        atl: Quantitative evaluation of the tibial tunnel after anterior cruciate ligament reconstruction using diffusion weighted and dynamic contrast enhanced MRI: a follow-up feasibility study.
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        au:
          Rupreht M
          Jevtic V
          Sersa I
          Vogrin M
          Seruga T
          Jevsek M
          Rupreht, Mitja
          Jevtič, Vladimir
          Serša, Igor
          Vogrin, Matjaž
          Seruga, Tomaž
          Jevšek, Marko
        affil: Radiology Department, University Medical Centre Maribor, Ljubljanska 5, 2000 Maribor, Slovenia
      sug:
        subj:
          Anterior Cruciate Ligament Reconstruction
          Image Enhancement Methods
          Magnetic Resonance Imaging Methods
          Postoperative Complications Diagnosis
          Tibia Pathology
          Adult
          Anterior Cruciate Ligament Injuries
          Contrast Media Diagnostic Use
          Edema Diagnosis
          Edema Etiology
          Pilot Studies
          Female
          Prospective Studies
          Graft Survival
          Human
          Male
          Postoperative Complications Etiology
          Postoperative Period
          Rupture Diagnosis
          Rupture Etiology
          Tibia Blood Supply
          Wound Healing
          Adult: 19-44 years
          Female
          Male
      ab: Objective: The aim of the study was to evaluate the feasibility of two quantitative MRI methods: diffusion weighted imaging (DWI) and dynamic contrast enhanced imaging (DCEI), for follow-up assessment of the tibial tunnel after reconstruction of the anterior cruciate ligament (ACL).Materials and Methods: Twenty-three patients were examined by MRI at 1 and 6 months following ACL reconstruction. DWI and DCEI were utilized for evaluating the region of interest (ROI) within the proximal part of the tibial tunnel. From the resulting apparent diffusion coefficient (ADC) maps, ADC values were calculated. DCEI data were used to extract the enhancement factor (f(enh)) and the enhancement gradient (g(enh)) for the same ROI.Results: Calculated ADC as well as the f(enh) and g(enh) had diminished to a statistically significant extent by 6 months after ACL reconstruction. The average ADC value diminished from 1.48 (10(-3) mm(2)/s) at 1 month to 1.30 (10(-3) mm(2)/s) at 6 months after reconstruction. The average f(enh) value decreased from 1.21 at 1 month to 0.50 at 6 months and the average g(enh) value decreased from 2.01%/s to 1.15%/s at 6 months, respectively.Conclusion: The study proved feasibility of DWI and DCEI for quantitative assessment of the tibial tunnel at 1 and 6 months after ACL reconstruction. Both methods have the potential for use as an additional tool in the evaluation of new methods of ACL reconstruction. To our knowledge, this is the first time quantitative MRI has been used in the follow-up to the ACL graft healing process.
      pubtype: Academic Journal
      doctype:
        research
        Journal Article
      ougenre: Article
    language: English
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