Group B streptococcus infection in neonatal intensive care unit.

Objective: To evaluate the characteristics and clinical course of the neonates with group B streptococcus (GBS) infection in neonatal intensive care unit (NICU). Material and Methods: Between January 2010 and December 2010, we retrospectively evaluated demographic features, treatment and clinical co...

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Published in:Turkiye Klinikleri Journal of Medical Sciences Vol. 32; no. 3; pp. 702 - 707
Main Authors: Dizdar, Evrim Alyamac, Sari, Fatma Nur, Özdemir, Ramazan, Uras, Nurdan, Erdeve, Ömer, Oguz, Serife Suna, Saygan, Sibel, Dilmen, Ugur
Format: research tables/charts Journal Article
Published: Turkiye Klinikleri Jun2012
Online Access:View this record in EBSCOhost
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      dt: Jun2012
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      pub: Turkiye Klinikleri
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        atl: Group B streptococcus infection in neonatal intensive care unit.
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          Dizdar, Evrim Alyamac
          Sari, Fatma Nur
          Özdemir, Ramazan
          Uras, Nurdan
          Erdeve, Ömer
          Oguz, Serife Suna
          Saygan, Sibel
          Dilmen, Ugur
      sug:
        subj:
          Intensive Care Units, Neonatal
          Streptococcal Infections Epidemiology
          Descriptive Statistics
          Dyspnea
          Female
          Fever
          Human
          Infant
          Male
          Pneumonia
          Retrospective Design
          Streptococcal Infections Symptoms
          Infant: 1-23 months
          Female
          Male
      ab: Objective: To evaluate the characteristics and clinical course of the neonates with group B streptococcus (GBS) infection in neonatal intensive care unit (NICU). Material and Methods: Between January 2010 and December 2010, we retrospectively evaluated demographic features, treatment and clinical course of patients with GBS infection. Diagnosis of GBS infection was made when blood cultures were positive for GBS plus clinical and/or laboratory findings also supported GBS infection. Results: Ten (7 males and 3 females) of 8055 patients (0.124%) had culture-proven GBS infection. The median gestational age was 36 years (range 26-40 years) and birth weight was 3015 gr (range 1000-3830 gr). The presenting symptom was dyspnea in 7 patients, feeding disturbance in one and fever in one patient. Infection site was pneumonia in 5 patients, meningitis in 1 patient and could not be detected in 4 patients. Treatment with penicillin G 400.000 u/kg/d was initiated in one patient with meningitis and 200.000 u/kg/d in the remaining patients. One premature infant died while the remaining 9 patients completely recovered and were discharged after hospitalization for a median of 12.5 days (range 3-55 days). Conclusion: This study showed the importance of considering GBS infection in differential diagnosis of newborns with dyspnea and initiating appropriate treatment as soon as possible. Early and rapid diagnosis and antibiotic treatment in appropriate doses provides control of GBS infections.
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        research
        tables/charts
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      ougenre: Article
    language: Turkish
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