The importance of tumor size in differentiated thyroid carcinomas.

Objective: We aimed to assess the correlation of tumor size with other risk parameters in differentiated thyroid carcinomas. Material and Methods: Data of patients diagnosed with thyroid carcinoma, underwent bilateral total/near total thyroidectomy and treated with high doses of 131I were examined r...

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Publicado en:Turkiye Klinikleri Journal of Medical Sciences Vol. 32; no. 3; pp. 733 - 739
Autores principales: Hasbek, Zekiye, Turgut, Bülent, Erselcan, Taner, Börksüz, Mehmet Fatih, Ymuk, Fadime
Formato: research tables/charts Journal Article
Publicado: Turkiye Klinikleri Jun2012
Acceso en línea:Ver este registro en EBSCOhost
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      dt: Jun2012
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      pub: Turkiye Klinikleri
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        atl: The importance of tumor size in differentiated thyroid carcinomas.
      aug:
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          Hasbek, Zekiye
          Turgut, Bülent
          Erselcan, Taner
          Börksüz, Mehmet Fatih
          Ymuk, Fadime
      sug:
        subj:
          Thyroid Neoplasms Physiopathology
          Female
          Human
          Male
          Middle Age
          Thyroid Neoplasms Prognosis
          Middle Aged: 45-64 years
          Female
          Male
      ab: Objective: We aimed to assess the correlation of tumor size with other risk parameters in differentiated thyroid carcinomas. Material and Methods: Data of patients diagnosed with thyroid carcinoma, underwent bilateral total/near total thyroidectomy and treated with high doses of 131I were examined retrospectively. In patients with tumor size </=1 cm and >1 cm, the correlation between the tumor size and histopathologic classification, gender, age, multifocality and lymph-node was assessed. Results: The study included 285 patients; 237 (83.2%) were female, 48 (16.8%) were male. Two hundred and forty five patients (86%) had papillary carcinoma. The tumor was </=1 cm in 6out of 23 male cases with a single focus (26.1%) and in 5 out of 14 male patients with multiple foic (35.7%). In those with tumor </=1 cm multifocality rate was higher. In 32 out of 97 (33%) patients with tumor size </=1 cm the tumor was multifocal, while in 46 out of 116 (39.7%) with tumor >1 cm there was uptake in many foci. For multifocality there was no significant difference for tumor size </=1 cm and >1 cm (p=0.31). Of 65 patients aged >/=45 with a single focus, tumor size was </=1 cm in 37 (56.9%), whereas in 21 out of 32 (65.6%) with multifocality, the tumor was </=1 cm. In the patient group aged >/= 45 the rate of multifocality was higher in those with tumor size </=1 cm than those with tumors >1 cm. Conclusion: Although in patients with tumor size </=1 cm and with no risk factor, lobectomy and isthmectomy is adequate and ablation therapy is not recommended, due to the high rate of multifocality, we suggest that total thyroidectomy and ablation therapy may be useful.
      pubtype: Academic Journal
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        research
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      ougenre: Article
    language: Turkish
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