Sitagliptin and acute pancreatitis: cases and literature review.

Acute pancreatitis is the rapid onset inflammation of the pancreas. Medications are rare but important and rising cause of acute pancreatitis and account for approximately 2% of all cases. Sitagliptin is a potent and selective dipeptidyl peptidase-4 (DPP-4) inhibitor for the treatment of patients wi...

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Bibliographic Details
Published in:Turkiye Klinikleri Journal of Medical Sciences Vol. 32; no. 3; pp. 859 - 865
Main Authors: Köroglu, Banu Kale, Songür, Yildiran, Ersoy, Ismail Hakki, Köroglu, Mert, Akin, Mete, Tamer, M. Numan
Format: case study diagnostic images Journal Article
Published: Turkiye Klinikleri Jun2012
Online Access:View this record in EBSCOhost
Description
Summary:Acute pancreatitis is the rapid onset inflammation of the pancreas. Medications are rare but important and rising cause of acute pancreatitis and account for approximately 2% of all cases. Sitagliptin is a potent and selective dipeptidyl peptidase-4 (DPP-4) inhibitor for the treatment of patients with type 2 diabetes mellitus and acts by increasing active incretin hormone concentrations. Adverse effects including constipation, nausea, nasopharyngitis, urinary tract infection and dizziness were reported. We reported a case with acute pancreatitis that seems to be induced by sitagliptin.