Impaired adenosine monophosphate-activated protein kinase signalling in dorsal root ganglia neurons is linked to mitochondrial dysfunction and peripheral neuropathy in diabetes.

Mitochondrial dysfunction occurs in sensory neurons and may contribute to distal axonopathy in animal models of diabetic neuropathy. The adenosine monophosphate-activated protein kinase and peroxisome proliferator-activated receptor γ coactivator-1α (PGC-1α) signalling axis senses the metabolic dema...

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Publicado en:	Brain: A Journal of Neurology Vol. 135; no. 6; pp. 1751 - 1767
Autores principales:	Roy Chowdhury SK, Smith DR, Saleh A, Schapansky J, Marquez A, Gomes S, Akude E, Morrow D, Calcutt NA, Fernyhough P, Roy Chowdhury, Subir K, Smith, Darrell R, Saleh, Ali, Schapansky, Jason, Marquez, Alexandra, Gomes, Suzanne, Akude, Eli, Morrow, Dwane, Calcutt, Nigel A, Fernyhough, Paul
Formato:	research Journal Article
Publicado:	Oxford University Press / USA Jun2012
Acceso en línea:	Ver este registro en EBSCOhost