Review of laser speckle-based analysis in medical imaging.

Speckle pattern forms when a rough object is illuminated with coherent light (laser) and the backscattered radiation is imaged on a screen. The pattern changes over time due to movement in the object. Such time-integrate speckle pattern can be statistically analyzed to reveal the flow profile. For h...

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Publicado en:Medical & Biological Engineering & Computing Vol. 50; no. 6; pp. 547 - 559
Autores principales: Basak K, Manjunatha M, Dutta PK, Basak, Kausik, Manjunatha, M, Dutta, Pranab Kumar
Formato: review Journal Article
Publicado: Springer Nature Jun2012
Acceso en línea:Ver este registro en EBSCOhost
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        atl: Review of laser speckle-based analysis in medical imaging.
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          Basak K
          Manjunatha M
          Dutta PK
          Basak, Kausik
          Manjunatha, M
          Dutta, Pranab Kumar
        affil: School of Medical Science and Technology, Indian Institute of Technology Kharagpur, Kharagpur 721302, India
      sug:
        subj:
          Diagnosis, Cardiovascular Methods
          Animals
          Blood Flow Velocity Physiology
          Cerebrovascular Circulation Physiology
          Image Interpretation, Computer Assisted Methods
          Microcirculation Physiology
          Skin Blood Supply
      ab: Speckle pattern forms when a rough object is illuminated with coherent light (laser) and the backscattered radiation is imaged on a screen. The pattern changes over time due to movement in the object. Such time-integrate speckle pattern can be statistically analyzed to reveal the flow profile. For higher velocity the speckle contrast gets reduced. This theory can be utilized for tissue perfusion in capillaries of human skin tissue and cerebral blood flow mapping in rodents. Early, the technique was suffered from low resolution and computational intricacies for real-time monitoring purpose. However, modern engineering has made it feasible for real-time monitoring in microcirculation imaging with improved resolution. This review illustrates several modifications over classical technique done by many researchers. Recent advances in speckle contrast methods gain major interest, leading towards practical implementation of this technique. The review also brings out the scopes of laser speckle-based analysis in various medical applications.
      pubtype: Academic Journal
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        review
        Journal Article
      ougenre: Article
    language: English
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