Valence Scaling of Dynamic Facial Expressions is Altered in High-Functioning Subjects with Autism Spectrum Disorders: an fMRI Study.
FMRI was performed with the dynamic facial expressions fear and happiness. This was done to detect differences in valence processing between 25 subjects with autism spectrum disorders (ASDs) and 27 typically developing controls. Valence scaling was abnormal in ASDs. Positive valence induces lower de...
| Publicado en: | Journal of Autism & Developmental Disorders Vol. 42; no. 6; pp. 1011 - 1025 |
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| Autores principales: | , , , , , , , , , , , , , , , , , , |
| Formato: | diagnostic images pictorial research tables/charts Journal Article |
| Publicado: |
Springer Nature
Jun2012
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=104451829&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 104451829 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 01623257 AUT jtl: Journal of Autism & Developmental Disorders issn: 01623257 maglogo: N pubinfo: dt: Jun2012 vid: 42 iid: 6 pid: 237 pub: Springer Nature place: New York, New York artinfo: ui: 104451829 76140768 10.1007/s10803-011-1332-8 NLM21822763 104451829 ppf: 1011 ppct: 14 formats: fmt: @attributes: type: P tig: atl: Valence Scaling of Dynamic Facial Expressions is Altered in High-Functioning Subjects with Autism Spectrum Disorders: an fMRI Study. aug: au: Rahko, Jukka Paakki, Jyri-Johan Starck, Tuomo Nikkinen, Juha Pauls, David Kätsyri, Jari Jansson-Verkasalo, Eira Carter, Alice Hurtig, Tuula Mattila, Marja-Leena Jussila, Katja Remes, Jukka Kuusikko-Gauffin, Sanna Sams, Mikko Bölte, Sven Ebeling, Hanna Moilanen, Irma Tervonen, Osmo Kiviniemi, Vesa affil: Institute of Clinical Medicine, Department of Child Psychiatry, University and University Hospital of Oulu, 90029 OYS Oulu Finland sug: subj: Magnetic Resonance Imaging Methods Autism Spectrum Disorder Facial Expression Emotions Human Finland Child Interview Guides Scales Questionnaires Record Review Interviews Comorbidity Male Female Adolescence Descriptive Statistics Data Analysis Software Funding Source Neurons Limbic System Child: 6-12 years Adolescent: 13-18 years Male Female ab: FMRI was performed with the dynamic facial expressions fear and happiness. This was done to detect differences in valence processing between 25 subjects with autism spectrum disorders (ASDs) and 27 typically developing controls. Valence scaling was abnormal in ASDs. Positive valence induces lower deactivation and abnormally strong activity in ASD in multiple regions. Negative valence increased deactivation in visual areas in subjects with ASDs. The most marked differences between valences focus on fronto-insular and temporal regions. This supports the idea that subjects with ASDs may have difficulty in passive processing of the salience and mirroring of expressions. When the valence scaling of brain activity fails, in contrast to controls, these areas activate and/or deactivate inappropriately during facial stimuli presented dynamically. pubtype: Academic Journal doctype: diagnostic images pictorial research tables/charts Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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