Diagnostic accuracy of fine-needle aspiration versus core-needle biopsy for the diagnosis of thyroid malignancy in a clinical cohort.
Objectives: To retrospectively compare the accuracy of fine-needle aspiration (FNA) and core-needle biopsy (CNB) for the diagnosis of thyroid malignancyMethods: We evaluated the results of FNA and CNB in 555 consecutive thyroid nodules with final diagnoses (malignancy 318, benign 237). All patients...
| Publicado en: | European Radiology Vol. 22; no. 7; pp. 1564 - 1573 |
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| Autores principales: | , , , , , , , , , , , , , |
| Formato: | research Journal Article |
| Publicado: |
Springer Nature
Jul2012
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=104454994&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 104454994 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 09387994 NPH jtl: European Radiology issn: 09387994 maglogo: N pubinfo: dt: Jul2012 vid: 22 iid: 7 pid: 237 pub: Springer Nature place: New York, New York artinfo: ui: 104454994 NLM22415411 2011569740 10.1007/s00330-012-2405-6 NLM22415411 104454994 ppf: 1564 ppct: 9 formats: fmt: @attributes: type: P tig: atl: Diagnostic accuracy of fine-needle aspiration versus core-needle biopsy for the diagnosis of thyroid malignancy in a clinical cohort. aug: au: Sung JY Na DG Kim KS Yoo H Lee H Kim JH Baek JH Sung, Jin Yong Na, Dong Gyu Kim, Kyu Sun Yoo, Hyunju Lee, Hunkyung Kim, Ji-Hoon Baek, Jung Hwan affil: Department of Radiology, Thyroid Center, Daerim St. Mary's Hospital, Seoul, South Korea sug: subj: Biopsy, Needle Methods Biopsy, Needle Statistics and Numerical Data Thyroid Neoplasms Epidemiology Thyroid Neoplasms Pathology Adult Female Human Male Prevalence Reproducibility of Results South Korea Sensitivity and Specificity Adult: 19-44 years Female Male ab: Objectives: To retrospectively compare the accuracy of fine-needle aspiration (FNA) and core-needle biopsy (CNB) for the diagnosis of thyroid malignancyMethods: We evaluated the results of FNA and CNB in 555 consecutive thyroid nodules with final diagnoses (malignancy 318, benign 237). All patients underwent FNA and CNB simultaneously for each nodule. We assessed the sensitivity, specificity and accuracy of FNA, CNB and FNA/CNB for the diagnosis of thyroid malignancy.Results: The sensitivity of FNA, CNB and FNA/CNB for thyroid malignancy was 68.6%, 86.8% and 90.6%, specificity 100%, 99.2% and 99.2%, and accuracy 82.0%, 92.1% and 94.2%, respectively. The sensitivity and accuracy of CNB or FNA/CNB for thyroid malignancy were significantly higher than those of FNA (P < 0.001). Compared with CNB alone, FNA/CNB was more accurate for thyroid malignancy only in small nodules less than 1 cm (P < 0.001).Conclusions: Our clinical cohort data demonstrated that CNB was more accurate for the diagnosis of thyroid malignancy than FNA, and FNA/CNB was more accurate than CNB alone in small thyroid nodules. CNB will play a complementary role in optimal surgical decision-making and the management of thyroid nodules.Key Points: • CNB was more accurate for the diagnosis of malignancy than FNA. • Combined FNA/CNB was more accurate than CNB alone in small thyroid nodules. • CNB should play at least a complementary role in managing thyroid nodules. pubtype: Academic Journal doctype: research Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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