Evaluation of preservative efficacy in pharmaceutical products: the use of psychrotolerant, low-nutrient preferring microbes in challenge tests.

What is known and Objective: Preservative efficacy in medicines is typically investigated using challenge tests. In such tests, the product is artificially contaminated with a high concentration of standard bacterial and fungal test strains such as Pseudomonas aeruginosa and Candida albicans. The ra...

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Detalles Bibliográficos
Publicado en:Journal of Clinical Pharmacy & Therapeutics Vol. 37; no. 5; pp. 558 - 565
Autores principales: Charnock, C., Otterholt, E.
Formato: research tables/charts Journal Article
Publicado: Wiley-Blackwell Oct2012
Acceso en línea:Ver este registro en EBSCOhost