A Canonical Biomechanical Vocal Fold Model.

Summary: The present article aimed at constructing a canonical geometry of the human vocal fold (VF) from subject-specific image slice data. A computer-aided design approach automated the model construction. A subject-specific geometry available in literature, three abstractions (which successively...

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Publicado en:Journal of Voice Vol. 26; no. 5; pp. 535 - 548
Autores principales: Bhattacharya, Pinaki, Siegmund, Thomas H.
Formato: Journal Article
Publicado: Elsevier B.V. Sep2012
Acceso en línea:Ver este registro en EBSCOhost
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      dt: Sep2012
      vid: 26
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      pub: Elsevier B.V.
      place: New York, New York
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        atl: A Canonical Biomechanical Vocal Fold Model.
      aug:
        au:
          Bhattacharya, Pinaki
          Siegmund, Thomas H.
        affil: School of Mechanical Engineering, Purdue University, West Lafayette, Indiana
      sug:
        subj:
          Models, Biological Evaluation
          Vocal Cords
          Computer-Aided Design
          Mathematics Methods
          Biomechanics
      ab: Summary: The present article aimed at constructing a canonical geometry of the human vocal fold (VF) from subject-specific image slice data. A computer-aided design approach automated the model construction. A subject-specific geometry available in literature, three abstractions (which successively diminished in geometric detail) derived from it, and a widely used quasi two-dimensional VF model geometry were used to create computational models. The first three natural frequencies of the models were used to characterize their mechanical response. These frequencies were determined for a representative range of tissue biomechanical properties, accounting for underlying VF histology. Compared with the subject-specific geometry model (baseline), a higher degree of abstraction was found to always correspond to a larger deviation in model frequency (up to 50% in the relevant range of tissue biomechanical properties). The model we deemed canonical was optimally abstracted, in that it significantly simplified the VF geometry compared with the baseline geometry but can be recalibrated in a consistent manner to match the baseline response. Models providing only a marginally higher degree of abstraction were found to have significant deviation in predicted frequency response. The quasi two-dimensional model presented an extreme situation: it could not be recalibrated for its frequency response to match the subject-specific model. This deficiency was attributed to complex support conditions at anterior-posterior extremities of the VFs, accentuated by further issues introduced through the tissue biomechanical properties. In creating canonical models by leveraging advances in clinical imaging techniques, the automated design procedure makes VF modeling based on subject-specific geometry more realizable.
      pubtype: Academic Journal
      doctype: Journal Article
      ougenre: Article
    language: English
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