Implant and Long-Term Evaluation of Atrial Signal Amplification in a Single-Lead ICD.
Background: In patients without clinical indications for pacing the use of a single-lead implantable cardioverter defibrillator (ICD) implementing atrial sensing capability with proper signal amplification management may represent a useful therapeutic option, combining the positive features of both...
| Publicado en: | Pacing & Clinical Electrophysiology Vol. 35; no. 9; pp. 1119 - 1126 |
|---|---|
| Autores principales: | , , , , , |
| Formato: | research tables/charts Journal Article |
| Publicado: |
Wiley-Blackwell
Sep2012
|
| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=104505440&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 104505440 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 01478389 4F8 jtl: Pacing & Clinical Electrophysiology issn: 01478389 maglogo: Y pubinfo: dt: Sep2012 vid: 35 iid: 9 pid: 480 pub: Wiley-Blackwell place: Malden, Massachusetts artinfo: ui: 104505440 79779198 10.1111/j.1540-8159.2012.03452.x NLM22734815 104505440 ppf: 1119 ppct: 7 formats: fmt: @attributes: type: P tig: atl: Implant and Long-Term Evaluation of Atrial Signal Amplification in a Single-Lead ICD. aug: au: Stazi, Filippo Mampieri, Massimo Cardinale, Mario Laudadio, M. Teresa Gargaro, Alessio Del Giudice, Giovanni Battista affil: Department of Cardiology, San Giovanni Addolorata Hospital, Rome, Italy; Centro per la Lotta contro l'Infarto (CLI) Foundation, Rome, Italy sug: subj: Atrial Fibrillation Prevention and Control Defibrillators, Implantable Equipment and Supplies Electrodes, Implanted Evaluation Tachycardia, Supraventricular Diagnosis Human Male Female Middle Age Descriptive Statistics Ventricular Ejection Fraction Data Analysis Software T-Tests Analysis of Variance Linear Regression Confidence Intervals Middle Aged: 45-64 years Male Female ab: Background: In patients without clinical indications for pacing the use of a single-lead implantable cardioverter defibrillator (ICD) implementing atrial sensing capability with proper signal amplification management may represent a useful therapeutic option, combining the positive features of both single and dual-chamber devices. The aim of the study was to evaluate the atrial signal amplification and its long-term stability in a single-lead ICD system adding atrial sensing to a standard single-chamber ICD. Methods: P-wave amplitudes were collected and compared at implant both with a conventional external device ('unfiltered' P wave) and telemetrically with the implanted ICD ('filtered' P wave). Filtered/unfiltered P-wave ratio (amplification factor, AmF) was evaluated at implant and during follow-up. Results: In 43 enrolled patients (38 men, age 64 ± 16 years), the mean filtered P wave at implant was significantly higher than the unfiltered P wave (3.85 ± 0.81 mV vs 2.0 ± 1.49 mV; P < 10−11), with a mean AmF value of 2.77 ± 1.62. In seven patients with atrial fibrillation at implant, the AmF was higher (4.62 ± 1.94) than in patients in sinus rhythm (2.41 ± 1.30; P < 0.001). A significant linear correlation was found between the inverse of P wave and the AmF (R = 0.82, P < 0.00001). In 25 patients followed for 384 ± 244 days, atrial undersensing was never documented and AmF did not change from implant (3.19 ± 1.82; P = 0.24), also in different body position and breathing conditions. Conclusions: The single-lead ICD system evaluated reliably amplified P-wave amplitudes by a factor of about three, maintaining this performance during the observed follow-up. (PACE 2012; 35:1119-1125) pubtype: Academic Journal doctype: research tables/charts Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
|---|