Predictors of unsuccessful magnetic resonance imaging scanning in older generalized anxiety disorder patients and controls.

A thorough understanding of the neurobiology of late life anxiety is likely to depend on the use of brain imaging techniques such as magnetic resonance imaging (MRI). Generalized anxiety disorder (GAD) is one of the most prevalent anxiety disorders in older adults, and is thus a focus for neurobiolo...

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Publicado en:Journal of Behavioral Medicine Vol. 35; no. 1; pp. 19 - 27
Autores principales: Mohlman, Jan, Eldreth, Dana, Price, Rebecca, Chazin, Daniel, Glover, Dorie
Formato: research tables/charts Journal Article
Publicado: Springer Nature Feb2012
Acceso en línea:Ver este registro en EBSCOhost
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      dt: Feb2012
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      pub: Springer Nature
      place: New York, New York
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        atl: Predictors of unsuccessful magnetic resonance imaging scanning in older generalized anxiety disorder patients and controls.
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          Mohlman, Jan
          Eldreth, Dana
          Price, Rebecca
          Chazin, Daniel
          Glover, Dorie
        affil: Department of Psychology, Rutgers University, 152 Frelinghuysen Road Piscataway 08854 USA
      sug:
        subj:
          Aging Psychosocial Factors
          Anxiety Psychosocial Factors
          Anxiety Disorders Diagnosis
          Anxiety Disorders Psychosocial Factors
          Magnetic Resonance Imaging Psychosocial Factors
          Human
          Aged
          Middle Age
          Male
          Female
          Descriptive Statistics
          Logistic Regression
          Questionnaires
          Interview Guides
          Self Report
          Analysis of Variance
          Post Hoc Analysis
          Fisher's Exact Test
          Chi Square Test
          Odds Ratio
          Funding Source
          Aged: 65+ years
          Middle Aged: 45-64 years
          Male
          Female
      ab: A thorough understanding of the neurobiology of late life anxiety is likely to depend on the use of brain imaging techniques such as magnetic resonance imaging (MRI). Generalized anxiety disorder (GAD) is one of the most prevalent anxiety disorders in older adults, and is thus a focus for neurobiological studies using MRI. This study tested 1-3 weeks predictors of unsuccessful scan outcomes (i.e., scan trials in which the participant moved excessively or prematurely terminated the scan) in older adults with GAD (n = 39) and age- and sex-matched nonanxious controls (n = 21). It was hypothesized that successful completion of a prior MRI scan, clinical status (GAD versus control), and scores on the Anxiety Sensitivity Index (ASI; Peterson et al. ), a measure tapping psychological aspects of medical interventions, would predict scan outcome when current diagnoses of claustrophobia were controlled. In logistic regression analyses, unsuccessful scan outcome was predicted by prior MRI completion and ASI Mental Concerns subscale scores, but not clinical status. This model correctly classified 91% of successful and 71% of unsuccessful scans. An alternative model that included a single ASI item rather than Mental Concerns subscale scores showed similar performance, and a model including categorical anxiety sensitivity groups was also effective but slightly less accurate. Implications for improving the success rates of MRI with older adults are discussed.
      pubtype: Academic Journal
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        research
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      ougenre: Article
    language: English
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