Lack of Correlation Between Metallic Elements Analyzed in Hair by ICP-MS and Autism.
A cross-sectional case-control study was carried out to evaluate the concentrations of metallic elements in the hair of 44 children with diagnosis of autism and 61 age-balanced controls. Unadjusted comparisons showed higher concentrations of molybdenum, lithium and selenium in autistic children. Log...
| Publicado en: | Journal of Autism & Developmental Disorders Vol. 42; no. 3; pp. 342 - 354 |
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| Autores principales: | , , , , |
| Formato: | research tables/charts Journal Article |
| Publicado: |
Springer Nature
Mar2012
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=104516621&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 104516621 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 01623257 AUT jtl: Journal of Autism & Developmental Disorders issn: 01623257 maglogo: N pubinfo: dt: Mar2012 vid: 42 iid: 3 pid: 237 pub: Springer Nature place: New York, New York artinfo: ui: 104516621 71707539 10.1007/s10803-011-1245-6 NLM21503799 104516621 ppf: 342 ppct: 12 formats: fmt: @attributes: type: P tig: atl: Lack of Correlation Between Metallic Elements Analyzed in Hair by ICP-MS and Autism. aug: au: De Palma, Giuseppe Catalani, Simona Franco, Anna Brighenti, Maurizio Apostoli, Pietro affil: Department of Experimental and Applied Medicine, Section of Occupational Health and Industrial Hygiene, University of Brescia, Piazzale Spedali Civili 1 25123 Brescia Italy sug: subj: Metals Analysis Autism Spectrum Disorder Etiology Hair Analysis Methods Environmental Exposure Risk Factors Cross Sectional Studies Case Control Studies Human Logistic Regression Male Female Child, Preschool Adolescence Child Descriptive Statistics Data Analysis Software Mann-Whitney U Test Post Hoc Analysis Type I Error Multivariate Analysis Confounding Variable Chelating Agents Confidence Intervals Odds Ratio Dietary Supplementation Nonparametric Statistics Kruskal-Wallis Test Spearman's Rank Correlation Coefficient Meta Analysis Sex Factors Alternative Therapies Child, Preschool: 2-5 years Adolescent: 13-18 years Child: 6-12 years Male Female ab: A cross-sectional case-control study was carried out to evaluate the concentrations of metallic elements in the hair of 44 children with diagnosis of autism and 61 age-balanced controls. Unadjusted comparisons showed higher concentrations of molybdenum, lithium and selenium in autistic children. Logistic regression analysis confirmed the role of risk factor for male gender and showed a slight association with molybdenum concentrations. Unconventional chelation and vitamin-mineral supplementation were ineffective on elemental hair concentrations. A meta-analysis including the present and previous similar studies excluded any association of autism with hair concentrations of mercury, cadmium, selenium, lithium and copper. A slight association was found for lead only, but it was very weak, as strictly dependent on the worst data from one study. pubtype: Academic Journal doctype: research tables/charts Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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