Design and Subject Characteristics in the Federally-Funded Citalopram Trial in Children with Pervasive Developmental Disorders.
The Studies to Advance Autism Research and Treatment Network conducted a randomized trial with citalopram in children with Pervasive developmental disorders (PDDs). We present the rationale, design and sample characteristics of the citalopram trial. Subjects (128 boys, 21 girls) had a mean age of 9....
| Publicado en: | Journal of Autism & Developmental Disorders Vol. 42; no. 3; pp. 432 - 441 |
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| Autores principales: | , , , , , , , , , , , , , , , |
| Formato: | research tables/charts randomized controlled trial Journal Article |
| Publicado: |
Springer Nature
Mar2012
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=104516632&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 104516632 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 01623257 AUT jtl: Journal of Autism & Developmental Disorders issn: 01623257 maglogo: N pubinfo: dt: Mar2012 vid: 42 iid: 3 pid: 237 pub: Springer Nature place: New York, New York artinfo: ui: 104516632 71707548 10.1007/s10803-011-1251-8 NLM21667200 104516632 ppf: 432 ppct: 9 formats: fmt: @attributes: type: P tig: atl: Design and Subject Characteristics in the Federally-Funded Citalopram Trial in Children with Pervasive Developmental Disorders. aug: au: Scahill, Lawrence McCracken, James Bearss, Karen Robinson, Fay Hollander, Eric King, Bryan Bregman, Joel Sikich, Lin Dukes, Kimberly Sullivan, Lisa Anagnostou, Evdokia Donnelly, Craig Kim, Young-Shin Ritz, Louise Hirtz, Deborah Wagner, Ann affil: Yale University School of Nursing and Child Study Center, 230 S. Frontage Rd. New Haven USA sug: subj: Child Development Disorders, Pervasive Drug Therapy Citalopram Administration and Dosage Human Child Male Female Double-Blind Studies Data Analysis Software Descriptive Statistics Funding Source Scales Neuropsychological Tests Intelligence Tests Severity of Illness Risperidone Therapeutic Use Treatment Outcomes Methylphenidate Therapeutic Use Parental Role Exploratory Research T-Tests Chi Square Test Financing, Government Multicenter Studies Randomized Controlled Trials Child: 6-12 years Male Female ab: The Studies to Advance Autism Research and Treatment Network conducted a randomized trial with citalopram in children with Pervasive developmental disorders (PDDs). We present the rationale, design and sample characteristics of the citalopram trial. Subjects (128 boys, 21 girls) had a mean age of 9.3 (±3.12) years; 132 (88.6%) were diagnosed with autistic disorder (4.7% with Asperger's Disorder; 6.7% with PDD-not otherwise specified). Less than half of the subjects were intellectually disabled; 117 (78.5%) were rated Moderate or Marked on the Clinical Global Impression for Severity. Study measures were similar to previous Research Units on Pediatric Psychopharmacology trials. Subjects in this trial were slightly older and more likely to have complaints of repetitive behavior than participants in RUPP trials. pubtype: Academic Journal doctype: research tables/charts randomized controlled trial Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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