How the blood pool properties at onset affect the temporal behavior of simulated bruises.

The influence of initial blood pool properties on the temporal behavior of bruises is currently unknown. We addressed this important issue by utilizing three typical classes of bruises in our three-layered finite compartment model. We simulated the effects of their initial shapes, regularity of boun...

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Publicado en:Medical & Biological Engineering & Computing Vol. 50; no. 2; pp. 165 - 172
Autores principales: Stam B, van Gemert MJ, van Leeuwen TG, Aalders MC, Stam, Barbara, Gemert, Martin J C van, Leeuwen, Ton G van, Aalders, Maurice C G
Formato: research Journal Article
Publicado: Springer Nature Feb2012
Acceso en línea:Ver este registro en EBSCOhost
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        atl: How the blood pool properties at onset affect the temporal behavior of simulated bruises.
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          Stam B
          van Gemert MJ
          van Leeuwen TG
          Aalders MC
          Stam, Barbara
          Gemert, Martin J C van
          Leeuwen, Ton G van
          Aalders, Maurice C G
        affil: Biomedical Engineering and Physics, Academic Medical Centre, P.O. Box 22660, 1100 DD Amsterdam, The Netherlands
      sug:
        subj:
          Contusions and Abrasions Blood
          Models, Biological
          Bilirubin Blood
          Contusions and Abrasions Pathology
          Hemoglobins Metabolism
          Human
          Time Factors
      ab: The influence of initial blood pool properties on the temporal behavior of bruises is currently unknown. We addressed this important issue by utilizing three typical classes of bruises in our three-layered finite compartment model. We simulated the effects of their initial shapes, regularity of boundaries and initial blood concentration distributions (gaussian vs. homogeneous) on the hemoglobin and bilirubin areas in the dermal top layer. Age determination of bruises with gaussian hemoglobin concentration was also addressed. We found that the initial blood pool properties strongly affect bruise behavior. We determined the age of a 200-h simulated bruise with gaussian hemoglobin concentration with 3 h uncertainty. In conclusion, bruise behavior depends non-intuitively on the initial blood pool properties; hence, a model that includes shape, area and concentration distribution at onset is indispensable. Future age determination, including inhomogeneous hemoglobin distributions, will likely be based on the presented method for gaussian distributions.
      pubtype: Academic Journal
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        research
        Journal Article
      ougenre: Article
    language: English
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