Implementation of targeted interventions to decrease antiretroviral-related errors in hospitalized patients.
Purpose. The implementation and effectiveness of targeted interventions aimed at decreasing the frequency of antiretroviralrelated errors in hospitalized patients with human immunodeficiency virus (HIV) are described. Summary. A prospective investigation conducted at the University of North Carolina...
| Published in: | American Journal of Health-System Pharmacy Vol. 69; no. 5; pp. 422 - 431 |
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| Main Authors: | , , |
| Format: | research tables/charts teaching materials Journal Article |
| Published: |
Oxford University Press / USA
3/1/2012
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| Online Access: | View this record in EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=104527211&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 104527211 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 10792082 1X3 jtl: American Journal of Health-System Pharmacy issn: 10792082 maglogo: N pubinfo: dt: 3/1/2012 vid: 69 iid: 5 pid: 622 pub: Oxford University Press / USA artinfo: ui: 104527211 72354272 10.2146/ajhp110172 NLM22345421 104527211 ppf: 422 ppct: 9 formats: fmt: @attributes: type: P tig: atl: Implementation of targeted interventions to decrease antiretroviral-related errors in hospitalized patients. aug: au: Daniels, Lindsay M. Raasch, Ralph H. Corbett, Amanda H. affil: Clinical Pharmacy Specialist--Infectious Diseases, Department of Pharmacy, University of North Carolina Hospitals, Chapel Hill sug: subj: Anti-Retroviral Agents Adverse Effects Medication Errors Prevention and Control Anti-Retroviral Agents Administration and Dosage Teaching Materials, Clinical Anti-HIV Agents Pharmacy Service Formularies Clinical Pharmacy Information Systems Drug Resistance Electronic Order Entry Drug Interactions Program Implementation Medication Systems Pharmacists Root Cause Analysis Human Adult Middle Age Male Female Inpatients North Carolina Drug Combinations Academic Medical Centers Quality Assurance Adult: 19-44 years Middle Aged: 45-64 years Male Female ab: Purpose. The implementation and effectiveness of targeted interventions aimed at decreasing the frequency of antiretroviralrelated errors in hospitalized patients with human immunodeficiency virus (HIV) are described. Summary. A prospective investigation conducted at the University of North Carolina Hospitals revealed a high rate of antiretroviral-related errors occurring on admission to the hospital and throughout a patient's hospital stay. The high frequency of errors emphasized the need for targeted interventions aimed at preventing these errors and quickly identifying and resolving errors that do occur. Several interventions aimed at decreasing this error rate were instituted, including the addition of computer alerts for incorrect doses and drug interactions to the pharmacy order-entry system, distribution of an educational pocket-sized card among the staff, addition of commercially available combination antiretroviral products to the hospital formulary, updates of the computerized prescriber-order-entry (CPOE) system to include common dosage defaults, involvement of the infectious diseases consultation service to evaluate prescribed regimens of newly admitted patients with HIV, and daily review of newly initiated antiretroviral regimens by a clinical pharmacist trained in HIV care. A follow-up analysis was conducted after these interventions were implemented to evaluate their effectiveness. Of the 78 patients identified during the postintervention analysis, 12 (15%) had at least one error in their initial drug regimen versus 49 patients (72%) in the preintervention study (p < 0.001). Conclusion. Antiretroviral medication error rates decreased after the implementation of targeted interventions that included distributing an educational pocket-sized card, adding alerts to the pharmacy order-entry system, incorporating default dosages into the CPOE system, and adding combination antiretrovirals to the formulary. pubtype: Academic Journal doctype: research tables/charts teaching materials Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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