Acute Clinical Evaluation of a Left Ventricular Automatic Threshold Determination Algorithm Based on Evoked Response Sensing.
Introduction: Automatic pacing threshold (AT) testing may simplify device follow-up and improve device longevity. This study's objective was to evaluate the performance of a left ventricular (LV) evoked response sensing-based AT algorithm, for cardiac resynchronization therapy (CRT) devices. Methods...
| Publicado en: | Pacing & Clinical Electrophysiology Vol. 35; no. 3; pp. 348 - 357 |
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| Autores principales: | , , , , , , , |
| Formato: | clinical trial research tables/charts tracings Journal Article |
| Publicado: |
Wiley-Blackwell
Mar2012
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=104527948&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 104527948 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 01478389 4F8 jtl: Pacing & Clinical Electrophysiology issn: 01478389 maglogo: Y pubinfo: dt: Mar2012 vid: 35 iid: 3 pid: 480 pub: Wiley-Blackwell place: Malden, Massachusetts artinfo: ui: 104527948 72416726 10.1111/j.1540-8159.2011.03287.x NLM22150299 104527948 ppf: 348 ppct: 9 formats: fmt: @attributes: type: P tig: atl: Acute Clinical Evaluation of a Left Ventricular Automatic Threshold Determination Algorithm Based on Evoked Response Sensing. aug: au: Kalahasty, Gautham Giudici, Michael Lobban, John Doshi, Rahul Delaney, Colleen Shome, Shibaji Gold, Michael R. Ellenbogen, Kenneth affil: Virginia Commonwealth University, Richmond, Virginia sug: subj: Evoked Potentials Heart Ventricle Rehabilitation, Cardiac Cardiac Pacing, Artificial Algorithms Human Multicenter Studies Clinical Trials Descriptive Statistics Fisher's Exact Test Electrocardiography United States Male Female Aged Aged, 80 and Over Data Analysis Software Confidence Intervals Aged: 65+ years Aged, 80 & over Male Female ab: Introduction: Automatic pacing threshold (AT) testing may simplify device follow-up and improve device longevity. This study's objective was to evaluate the performance of a left ventricular (LV) evoked response sensing-based AT algorithm, for cardiac resynchronization therapy (CRT) devices. Methods: Patients scheduled for CRT-D/P implant were enrolled. A manual step-down threshold test and a Left Ventricular Automatic Threshold (LVAT) test in each of four pacing vectors-LVTip→Can, LVTip→right ventricle (RV), = LVRing→Can, and LVRing→RV-were conducted. Patients were randomized to either 0.4-ms or 1.0-ms pacing pulse width and in the manual and LVAT test order. A blinded core lab electrophysiologist (EP) determined the threshold using the surface electrocardiogram (gold standard). Results: Data from 70 patients were analyzed. Bipolar LV leads from three major manufacturers were used. A total of 273 AT tests were performed; 12 AT tests did not result in a threshold due to improper testing conditions. Of 261 eligible tests, 234 AT tests (89.6%) returned a threshold measurement. Of the 234 tests, in 233 tests (99.5%) the algorithm-determined threshold matched the EP-determined threshold for that test. A total of 16,689 capture and 526 noncapture beats were collected and the accuracy for detecting capture and noncapture were 98.5% and 99.7% with a two-sided 95% confidence level of (98.4%, 98.7%) and (99.4%, 100%), respectively. No AT threshold measurement was lower than the EP-determined threshold. Conclusion: In this study, the results suggest that the LVAT algorithm is accurate at determining pacing thresholds in multiple pacing configurations and a wide range of LV leads in CRT-D/P patients. (PACE 2011;1-5) pubtype: Academic Journal doctype: clinical trial research tables/charts tracings Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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