Construction, characterization, and preliminary BAC-end sequence analysis of a bacterial artificial chromosome library of the tea plant (Camellia sinensis)

We describe the construction and characterization of a publicly available BAC library for the tea plant, Camellia sinensis. Using modified methods, the library was constructed with the aim of developing public molecular resources to advance tea plant genomics research. The library consists of a tota...

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Publicado en:Journal of Biomedicine & Biotechnology pp. 476723 - 476724
Autores principales: Lin, Jinke, Kudrna, Dave, Wing, Rod A
Formato: Journal Article
Publicado: Wiley-Blackwell 2011
Acceso en línea:Ver este registro en EBSCOhost
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      dt: 2011
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      pub: Wiley-Blackwell
      place: Malden, Massachusetts
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        atl: Construction, characterization, and preliminary BAC-end sequence analysis of a bacterial artificial chromosome library of the tea plant (Camellia sinensis)
      aug:
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          Lin, Jinke
          Kudrna, Dave
          Wing, Rod A
        affil: School of Plant Sciences, Arizona Genomics Institute, The University of Arizona, Tucson AZ 85721, USA.
      sug:
        subj:
          Green Tea
          Chromosomes
          Genes
          Sequence Analysis Methods
          DNA
          Genome
          Mutation
      ab: We describe the construction and characterization of a publicly available BAC library for the tea plant, Camellia sinensis. Using modified methods, the library was constructed with the aim of developing public molecular resources to advance tea plant genomics research. The library consists of a total of 401,280 clones with an average insert size of 135 kb, providing an approximate coverage of 13.5 haploid genome equivalents. No empty vector clones were observed in a random sampling of 576 BAC clones. Further analysis of 182 BAC-end sequences from randomly selected clones revealed a GC content of 40.35% and low chloroplast and mitochondrial contamination. Repetitive sequence analyses indicated that LTR retrotransposons were the most predominant sequence class (86.93%-87.24%), followed by DNA retrotransposons (11.16%-11.69%). Additionally, we found 25 simple sequence repeats (SSRs) that could potentially be used as genetic markers.
      pubtype: Academic Journal
      doctype: Journal Article
      ougenre: Article
    language: English
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