Continuous production of lipase-catalyzed biodiesel in a packed-bed reactor: optimization and enzyme reuse study.

An optimal continuous production of biodiesel by methanolysis of soybean oil in a packed-bed reactor was developed using immobilized lipase (Novozym 435) as a catalyst in a tert-butanol solvent system. Response surface methodology (RSM) and Box-Behnken design were employed to evaluate the effects of...

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Publicado en:Journal of Biomedicine & Biotechnology pp. 950725 - 950726
Autores principales: Chen, Hsiao-Ching, Ju, Hen-Yi, Wu, Tsung-Ta, Liu, Yung-Chuan, Lee, Chih-Chen, Chang, Cheng, Chung, Yi-Lin, Shieh, Chwen-Jen
Formato: research Journal Article
Publicado: Wiley-Blackwell 2011
Acceso en línea:Ver este registro en EBSCOhost
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      pub: Wiley-Blackwell
      place: Malden, Massachusetts
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        atl: Continuous production of lipase-catalyzed biodiesel in a packed-bed reactor: optimization and enzyme reuse study.
      aug:
        au:
          Chen, Hsiao-Ching
          Ju, Hen-Yi
          Wu, Tsung-Ta
          Liu, Yung-Chuan
          Lee, Chih-Chen
          Chang, Cheng
          Chung, Yi-Lin
          Shieh, Chwen-Jen
        affil: Department and Graduate Program of Bioindustry Technology, Dayeh University, Chang-Hua, Taiwan.
      sug:
        subj:
          Energy-Generating Resources
          Biotechnology
          Enzymes Metabolism
          Lipase Metabolism
          Analysis of Variance
          Enzymes
          Equipment Reuse
          Lipase
          Models, Theoretical
          Regression
          Soybean Oil Metabolism
          Temperature
      ab: An optimal continuous production of biodiesel by methanolysis of soybean oil in a packed-bed reactor was developed using immobilized lipase (Novozym 435) as a catalyst in a tert-butanol solvent system. Response surface methodology (RSM) and Box-Behnken design were employed to evaluate the effects of reaction temperature, flow rate, and substrate molar ratio on the molar conversion of biodiesel. The results showed that flow rate and temperature have significant effects on the percentage of molar conversion. On the basis of ridge max analysis, the optimum conditions were as follows: flow rate 0.1 mL/min, temperature 52.1°C, and substrate molar ratio 1 : 4. The predicted and experimental values of molar conversion were 83.31 ± 2.07% and 82.81 ± .98%, respectively. Furthermore, the continuous process over 30 days showed no appreciable decrease in the molar conversion. The paper demonstrates the applicability of using immobilized lipase and a packed-bed reactor for continuous biodiesel synthesis.
      pubtype: Academic Journal
      doctype:
        research
        Journal Article
      ougenre: Article
    language: English
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