A Trojan Horse in Intensive Care Unit: Toxoplasma gondii.
ABS TRACT Ob jec ti ve: Toxoplasmosis attains clinical significance as an opportunistic infection with high mortality in immunosuppressed individuals. The aim of this study was to assess the anti-Toxoplasma gondii antibody seropositivity rate in intensive care unit patients (ICU) who are immunosuppr...
| Publicado en: | Turkiye Klinikleri Journal of Medical Sciences Vol. 32; no. 1; pp. 120 - 124 |
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| Autores principales: | , , , , , , |
| Formato: | research tables/charts Journal Article |
| Publicado: |
Turkiye Klinikleri
Feb2012
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=104544649&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 104544649 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 13000292 1VOP jtl: Turkiye Klinikleri Journal of Medical Sciences issn: 13000292 maglogo: N pubinfo: dt: Feb2012 vid: 32 iid: 1 pid: 67298 pub: Turkiye Klinikleri artinfo: ui: 104544649 2011503893 10.5336/medsci.2011-23054 104544649 ppf: 120 ppct: 4 formats: fmt: @attributes: type: P tig: atl: A Trojan Horse in Intensive Care Unit: Toxoplasma gondii. aug: au: Can, Özlem Selvi Yalçin, Saban Özgencil, Enver Oba, Sirali Ünal, Necmettin Oral, Mehmet Serdaroglu, Hacer affil: Department of Anesthesiology and Reanimation, Ankara University Faculty of Medicine, Ankara sug: subj: Intensive Care Units Toxoplasmosis Epidemiology Adult Antibodies Blood Chi Square Test Data Analysis Software Enzyme-Linked Immunosorbent Assay Epidemiology, Molecular Female Human Male Middle Age P-Value Seroprevalence Studies Toxoplasmosis Microbiology Adult: 19-44 years Middle Aged: 45-64 years Female Male ab: ABS TRACT Ob jec ti ve: Toxoplasmosis attains clinical significance as an opportunistic infection with high mortality in immunosuppressed individuals. The aim of this study was to assess the anti-Toxoplasma gondii antibody seropositivity rate in intensive care unit patients (ICU) who are immunosuppressed due to underlying critical illness. Material and Methods: One hundred and three (51 males, 52 females) patients in intensive care units and 78 healthy volunteers (39 males, 39 females) were enrolled in the study. Blood samples were collected from all patients within the first 24 hours of hospitalization in the ICU and anti-T. gondii IgG and IgM antibodies were tested by enzyme-linked immunosorbent assay. Results: IgG antibodies to T. gondii were positive in 58 (56.3%) patients in the ICU and in 19 (24.3%) healthy volunteers. IgM antibodies were positive in 15 patients (13.8%) in the ICU and in five healthy volunteers (6.4%) in the control group. The difference in the IgG seropositivity rate between the patient and the control group was statistically significant (p< 0.05). The seropositivity rate of anti-T.gondii IgM was higher in the patient group with no significance (p> 0.05). Conclusion: Toxoplasma seropositivity is common in ICU patients. Toxoplasmosis should be considered in immunosuppressed patients in the ICU and serological screening may be performed to prevent severe toxoplasmosis. pubtype: Academic Journal doctype: research tables/charts Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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